SRP2122

CTF1, GST tagged human

recombinant, expressed in E. coli, ≥70% (SDS-PAGE)

• Sinonimo/i: CTF, CTF/NFI, NF-1, NF-I
• Codice UNSPSC: 12352202
• NACRES: NA.26

Proprietà

• Origine biologica: human
• Ricombinante: expressed in E. coli
• Saggio: ≥70% (SDS-PAGE)
• Forma fisica: frozen liquid
• PM: ~36.8 kDa
• Confezionamento: pkg of 10 μg
• Concentrazione: 650 μg/mL
• Colore: colorless to clear
• N° accesso NCBI: X12492
• N° accesso UniProt: Q16619
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −70°C
• Informazioni sul gene: human herpesvirus 2 ... CTF-1(1489)

Descrizione

Azioni biochim/fisiol

The CCAAT-box binding protein 1 (CTF1, also called NF-I or NF-1) is a proline-rich transcription activator. It selectively activates transcription of genes that contain GCCAAT consensus sequence in the promoter region, including human Ha-Ras, alpha-globin, hsp70 and many other cellular and viral genes. Cloning and functional characterization of the protein revealed that CTF1 contains a N-terminal DNA binding domain and a C-terminal proline-rich activation domain. CTF1 was shown to interact with the general transcription factor IIB (TFIIB) and facilitate the recruitment of TFIIB to TBP-DNA complexes, with the forkhead thyroid transcription factor TTF2 to regulate hormone-dependent transcription of thyroperoxidase gene, as well as other receptor proteins to synergize hormone receptor-responsive activation.

Stato fisico

Clear and colorless frozen liquid solution

Nota sulla preparazione

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable