SRP0327

PADI-2 human

recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE)

• Sinonimo/i: Peptidyl arginine deiminase, type II
• Codice UNSPSC: 12352200
• NACRES: NA.77

Proprietà

• Origine biologica: human
• Ricombinante: expressed in baculovirus infected Sf9 cells
• Saggio: ≥60% (SDS-PAGE)
• Stato: aqueous solution
• PM: 77 kDa
• Confezionamento: pkg of 10 μg
• N° accesso NCBI: NM_007365
• N° accesso UniProt: Q9Y2J8
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −70°C
• Informazioni sul gene: human ... PADI2(11240)

Descrizione

Descrizione generale

Human PADI2, also known as Peptidyl arginine deiminase, type II, (GenBank Accession No. NM_007365), amino acids 1-665 (end) with C-terminal FLAG-tag, MW= 77kDa, expressed in a Baculovirus infected Sf9 cell expression system. Peptidyl arginine deiminase, protein-2 (PADI2) is mapped to human chromosome 1p36. It is expressed in Sertoli cells at the time of testicular development.

Applicazioni

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. PADI-2 human has been used in in vitro binding assays.

Azioni biochim/fisiol

Peptidyl arginine deiminase, protein-2 (PADI2) promotes protein citrullination and represses the multiplication of cells. It helps to transform the amino acid arginine in a protein into amino acid citrulline. PADI2 participates in epigenetic mechanisms. It is linked with rheumatoid arthritis.

Stato fisico

Formulated in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 80 ng/uL Flag peptide, 3 mMDTT, and 20% Glycerol.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable