SMB01042

Allocryptopin

≥90% (LC/MS-ELSD)

• Sinonimo/i: β-Allocryptopine, γ-Homochelidonine, Fagarine I
• Formula empirica (notazione di Hill): C₂₁H₂₃NO₅
• Numero CAS: 24240-04-8
• Peso molecolare: 369.41
• Numero MDL: MFCD00022318
• Codice UNSPSC: 12352205
• NACRES: NA.25

Proprietà

• Origine biologica: plant
• Saggio: ≥90% (LC/MS-ELSD)
• Stato: solid
• PM: 369.41
• Solubilità: water: slightly soluble
• applicazioni: metabolomics; vitamins, nutraceuticals, and natural products
• Temperatura di conservazione: −20°C
• Stringa SMILE: N1(CCc2c(cc4c(c2)OCO4)C(=O)Cc3c(c(c(cc3)OC)OC)C1)C
• InChI: 1S/C21H23NO5/c1-22-7-6-14-9-19-20(27-12-26-19)10-15(14)17(23)8-13-4-5-18(24-2)21(25-3)16(13)11-22/h4-5,9-10H,6-8,11-12H2,1-3H3; HYBRYAPKQCZIAE-UHFFFAOYSA-N

Descrizione

Descrizione generale

Allocryptopin, an isoquinoline alkaliod, is a natural product commonly available from Allocryptopinus japonicus, Glaucium arabicum, Zanthoxylum beecheyanum, Berberis integerrima, and Macleaya cordata. This secondary metabolite derived from plant sources exhibits various biological activities such as anti-inflammatory, antiviral, and antitumor properties.

Applicazioni

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Azioni biochim/fisiol

Allocryptopine has been reported to possess strong antibacterial, anti-inflammatoty, antiparasitic, antineoplastic and anti-addictive activities. Allocryptopine inhibits human acetylcholinesterase and butyrylcholinesterase. It blocks hERG current in HEK293 cells. Allocryptopine strongly enhanced the I(peak) of the T353I channel by enhancing the plasma membrane (PM) expression of Nav1.5 and rescued defective trafficking after co-incubation with HEK293 cells that carry mutation channel 24 h.

Caratteristiche e vantaggi

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Altre note

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Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable