SCP0176
KISS-1 68-91
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About This Item
Formula empirica (notazione di Hill):
C98H157N31O37
Peso molecolare:
2361.48
Codice UNSPSC:
12352202
NACRES:
NA.32
Saggio
≥95% (HPLC)
Forma fisica
lyophilized
Composizione
Peptide Content, ≥75%
Condizioni di stoccaggio
protect from light
Temperatura di conservazione
−20°C
Amino Acid Sequence
Gly-Thr-Ser-Leu-Ser-Pro-Pro-Pro-Glu-Ser-Ser-Gly-Ser-Arg-Gln-Gln-Pro-Gly-Leu-Ser-Ala-Pro-His-Ser
Applicazioni
Kisspeptins are a family of peptides encoded by the KISS-1 gene that are involved in GPR54 mediated cell signaling. Kiss-1 gene products are involved in metastasis suppression and the regulation of gonadotropin-releasing hormone (GnRH) secretion. A variety of kisspeptin peptides are available for use to study their unique functions.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
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E Papaoiconomou et al.
In vivo (Athens, Greece), 25(3), 343-354 (2011-05-18)
The Kiss-1 gene encodes a secreted protein that is proteolytically cleaved to produce a number of structurally related peptides, with high interspecies conservation, globally termed kisspeptins. The original niche for the role of kisspeptin in human physiology is derived from
Rafael Pineda et al.
Progress in brain research, 181, 55-77 (2010-05-19)
Reproductive maturation and function are maintained by a complex neurohormonal network that integrates at the so-called hypothalamic-pituitary-gonadal (HPG) axis. This system is hierarchically controlled by the decapeptide, GnRH, which in turn is under the dynamic regulation of multiple stimulatory and
Jenny Clarkson et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 28(35), 8691-8697 (2008-08-30)
Kisspeptin and its receptor GPR54 have recently been identified as key signaling partners in the neural control of fertility in animal models and humans. The gonadotropin-releasing hormone (GnRH) neurons represent the final output neurons of the neural network controlling fertility
Naresh Kumar Hanchate et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(3), 932-945 (2012-01-21)
Reproduction is controlled in the brain by a neural network that drives the secretion of gonadotropin-releasing hormone (GnRH). Various permissive homeostatic signals must be integrated to achieve ovulation in mammals. However, the neural events controlling the timely activation of GnRH
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