SAB4504560

Anti-phospho-Tau (pThr¹⁸¹) antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: Anti-DDPAC, Anti-FTDP-17, Anti-MAPTL, Anti-MSTD, Anti-MTBT1, Anti-MTBT2, Anti-PPND, Anti-PPP1R103, Anti-TAU, Anti-tau-40
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: antigen 78 kDa
• Reattività contro le specie: rat, human, mouse
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 1:20000; western blot: 1:500-1:1000
• N° accesso NCBI: P10636
• N° accesso UniProt: P10636
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pThr181)
• Informazioni sul gene: human ... MAPT(4137)

Descrizione

Descrizione generale

MAPT (microtubule associated protein tau) is located on human chromosome 17q21.3. This gene is expressed in neurons but is most prominent in axons.

Immunogeno

The antiserum was produced against synthesized peptide derived from human Tau around the phosphorylation site of Thr181.

Immunogen Range: 471-520

Azioni biochim/fisiol

MAPT (microtubule associated protein tau) participates in the pathology of Alzheimer′s disease (AD). It helps in the assembly and maintenance of microtubule structure. Removal of MAPT results in developmental delay and learning disability.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable