SAB4503839

Anti-phospho-SYK (pTyr⁵²⁵) antibody produced in rabbit

affinity isolated antibody

• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Stato: buffered aqueous solution
• PM: antigen 72 kDa
• Reattività contro le specie: mouse, rat, human
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• N° accesso NCBI: P43405
• N° accesso UniProt: P43405
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pTyr525)
• Informazioni sul gene: human ... SYK(6850)

Descrizione

Descrizione generale

Spleen tyrosine kinase (SYK) is a member of the non-receptor tyrosine kinase family. It is usually expressed in epithelial breast tissues and hematopoietic cells. SYK is mapped to human chromosome 9q22.

Immunogeno

The antiserum was produced against synthesized peptide derived from human SYK around the phosphorylation site of Tyr525.

Immunogen Range: 491-540

Applicazioni

Anti-phospho-SYK (pTyr525) antibody has been used in immunohistochemistry.

Azioni biochim/fisiol

Spleen tyrosine kinase (SYK), as a tumor suppressor gene helps to prevent the development and metastasis of breast cancer cells. It participates in B-cell receptor signaling. This protein helps to phosphorylate the α-tubulin subunits of microtubules.

Caratteristiche e vantaggi

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Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable