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SAB4503300

Sigma-Aldrich

Anti-TAS1R3 antibody produced in rabbit

affinity isolated antibody

Sinonimo/i:

Sweet taste receptor T1R3

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

PM

antigen 93 kDa

Reattività contro le specie

human

Concentrazione

~1 mg/mL

tecniche

ELISA: 1:10000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000

N° accesso NCBI

Q7RTX0

N° accesso UniProt

Q7RTX0

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... TAS1R3(83756)

Descrizione generale

Taste receptor family 1 member 3 (TAS1R3) gene encodes for sweet taste receptor T1R3 protein. T1R3 protein belongs to the family of 3 subtypes of G-protein coupled receptors (GPCRs). This protein is localized in the taste bud cells of the oral cavity. The TAS1R3 gene is mapped on the human chromosome at 1p36.33.

Immunogeno

The antiserum was produced against synthesized peptide derived from human TAS1R3.

Immunogen Range: 326-375

Applicazioni

Anti-TAS1R3 antibody produced in rabbit has been used in immunohistochemistry and immunocytochemistry.

Azioni biochim/fisiol

Sweet taste receptor T1R3 protein plays a role in membrane glucose sensing and regulates glucose homeostasis in endocrine cells..

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

nwg

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac.
Max, et al.
Nature Genetics, 28, 58-63 (2019)
Marco Tizzano et al.
Chemical senses, 40(9), 655-660 (2015-09-25)
The morphology of the vallate papillae from postmortem human samples was investigated with immunohistochemistry. Microscopically, taste buds were present along the inner wall of the papilla, and in some cases in the outer wall as well. The typical taste cell
Vladimir O Murovets et al.
PloS one, 10(6), e0130997-e0130997 (2015-06-25)
The G-protein-coupled sweet taste receptor dimer T1R2/T1R3 is expressed in taste bud cells in the oral cavity. In recent years, its involvement in membrane glucose sensing was discovered in endocrine cells regulating glucose homeostasis. We investigated importance of extraorally expressed

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