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SAB4502905

Sigma-Aldrich

Anti-Synapsin, N-Terminal antibody produced in rabbit

affinity isolated antibody

Sinonimo/i:

Brain protein 4.1, SYN-1, synapsin I

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About This Item

Numero MDL:
Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

PM

antigen 74 kDa

Reattività contro le specie

mouse, rat, human

Concentrazione

~1 mg/mL

tecniche

ELISA: 1:20000
western blot: 1:500-1:1000

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... SYN1(6853)

Categorie correlate

Descrizione generale

Anti-Synapsin Antibody detects endogenous levels of total Synapsin protein.
Synapsin I (SYN1) is a synaptic vesicle associated protein. It is present in the central nervous system like olfactory bulb, cerebral cortex, hippocampus, basal ganglia, thalamus, hypothalamus, cerebellum, pons-medulla, spinal cord and posterior pituitary gland. The protein is found in the nucleus and cytoplasm of granule cells, and in the glomerular synaptic complex of the cerebellum. SYN1 gene is located in human chromosome Xp11.3.

Immunogeno

The antiserum was produced against synthesized peptide derived from human Synapsin.

Immunogen Range: 3-52

Applicazioni

Anti-Synapsin, N-Terminal antibody has been used in immunohistochemistry.

Azioni biochim/fisiol

Synapsin I (SYN1) plays an important role in neurotransmitter release, exocytosis of the synaptic vesicles, neurite elongation and synaptogenesis. Brain dysfunction occurs due to improper expression of synapsin I.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

nwg

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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A novel method to derive and expand mice neural stem cells efficiently without neuro-sphere formation.
Ma ZZ, et al.
International Journal of Clinical and Experimental Medicine, 8(8), 12834?12841-12834?12841 (2015)
Increased synapsin I expression in cerebral malaria.
Thonsranoi K, et al.
International Journal of Clinical and Experimental Pathology, 8(11), 13996?14004-13996?14004 (2015)
Evidence for a Turner syndrome locus or loci at Xp11. 2-p22. 1.
Zinn AR, et al.
American Journal of Human Genetics, 63(6), 1757-1766 (1998)
Zhi-Zhao Ma et al.
International journal of clinical and experimental medicine, 8(8), 12834-12841 (2015-11-10)
Neural stem cells (NSCs) are multi-potent stem cells able to self-renew and generate immature and differentiated cell populations by asymmetric division. The NSCs are of considerable interest for cell replacement in neuro-degenerative diseases. NSCs are usually identified and expanded by
Alexandra Reichova et al.
Molecular and cellular endocrinology, 518, 110924-110924 (2020-07-04)
Oxytocin has been suggested as a potential therapeutic agent in autism and other neuropsychiatric conditions. Although, the link between the deficit in "SH3 domain and ankyrin repeat containing protein 3" (SHANK3) and autism spectrum disorders is highly studied topic, developmental

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