SAB4500363

Anti-Collagen I α2 antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: α 2 type i collagen, co1a2, col1a2, collagen, type i
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: antigen 129 kDa
• Reattività contro le specie: human
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 1:20000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• N° accesso NCBI: P08123
• N° accesso UniProt: P08123
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... COL1A2(1278)

Descrizione

Descrizione generale

Anti-Collagen I α2 Antibody detects endogenous levels of total Collagen I α2 protein.

Collagen I α2 (COL1A2) is located on human chromosome 7q22.1. Human COL1A2 gene consists of two dinucleotide repeats: one in the 5′-flanking region of the gene, made of of poly(dC–dA) and poly(dC–dG) and the other in the first intron comprised of poly(dG–dT).

Immunogeno

The antiserum was produced against synthesized peptide derived from human Collagen I alpha2.

Immunogen Range: 471-520

Applicazioni

Anti-Collagen I α2 antibody has been used to quantify protein expression levels after western blotting.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Azioni biochim/fisiol

Collagen I α2 (COL1A2) is essential to maintain elasticity of the vessel wall and is an important constituent of the extracellular matrix. Mutations in COL1A2 results in osteogenesis imperfecta (OI).

Caratteristiche e vantaggi

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Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable