SAB4301399

Anti-phospho-DRP1 (pSer⁶³⁷) antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: DLP1, DNM1L, DRP1, DVLP, Dymple
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: 82 kDa
• Reattività contro le specie: human
• Concentrazione: 1.0 mg/mL
• tecniche: western blot: 1:500-1:1000 (Cell Lysate)
• Isotipo: IgG
• Numero d’accesso: NP_036192.2.
• N° accesso UniProt: O00429
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pSer637)
• Informazioni sul gene: human ... DNM1L(10059)

Descrizione

Descrizione generale

Dynamin related protein 1 (DRP1) is a dynamin-related guanosine triphosphatase. The gene is located on human chromosome 12p11.21. DRP1 is a cytosolic protein, which is also present on the outer mitochondrial membrane.

Specificità

The antibody detects endogenous levels of DRP1 only when phosphorylated at serine 637.

Immunogeno

Peptide sequence around phosphorylation site of Serine637(K-L-S(p)-A-R) derived from Human DRP1.

Applicazioni

Anti-phospho-DRP1 (pSer⁶³⁷) antibody produced in rabbit has been used in immunoblotting and western blotting.

Azioni biochim/fisiol

Dynamin related protein 1 (DRP1) is an important regulator of mitochondrial fission and peroxisomal division. It regulates proper mitochondrial function, apoptosis and necrosis. Mutations in this gene is associated with Alzheimer′s disease.

Caratteristiche e vantaggi

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Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable