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Merck
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SAB4300614

Sigma-Aldrich

Anti-ARNTL antibody produced in rabbit

affinity isolated antibody

Sinonimo/i:

Anti-BMAL1 antibody produced in rabbit, Anti-BMAL1c antibody produced in rabbit, Anti-JAP3 antibody produced in rabbit, Anti-MGC47515 antibody produced in rabbit, Anti-aryl hydrocarbon receptor nuclear translocator-like antibody produced in rabbit

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About This Item

Numero MDL:
MFCD02262590
Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

PM

~69 kDa

Reattività contro le specie

rat, mouse, human

Concentrazione

1 mg/mL

tecniche

western blot: 1:500-1:1000

Isotipo

IgG

Sequenza immunogenica

(S-S-S-I-L)

N° accesso NCBI

NP_001025443.1

N° accesso UniProt

O00327

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... ARNTL(406)

Immunogeno

Peptide sequence around aa. 569-573 (S-S-S-I-L), according to the protein ARNTL.

Applicazioni

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Descrizione del bersaglio

ARNTL-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins.

Stato fisico

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Brian A Hodge et al.
Skeletal muscle, 5, 17-17 (2015-05-23)
Skeletal muscle is a major contributor to whole-body metabolism as it serves as a depot for both glucose and amino acids, and is a highly metabolically active tissue. Within skeletal muscle exists an intrinsic molecular clock mechanism that regulates the
Brian A Hodge et al.
eLife, 8 (2019-02-23)
In the present study we show that the master myogenic regulatory factor, MYOD1, is a positive modulator of molecular clock amplitude and functions with the core clock factors for expression of clock-controlled genes in skeletal muscle. We demonstrate that MYOD1
Michael L Rossetti et al.
American journal of physiology. Endocrinology and metabolism, 317(4), E631-E645 (2019-07-31)
Androgen depletion in humans leads to significant atrophy of the limb muscles. However, the pathways by which androgens regulate limb muscle mass are unclear. Our laboratory previously showed that mitochondrial degradation was related to the induction of autophagy and the

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