SAB4300257

Anti-phospho-Th (pSer¹⁹) antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: Anti-The antibody produced in rabbit, Anti-tyrosine hydroxylase antibody produced in rabbit
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: 55-60 kDa
• Reattività contro le specie: human, rat
• Concentrazione: 1 mg/mL
• tecniche: indirect immunofluorescence: 1:100-1:200
• Isotipo: IgG
• Sequenza immunogenica: (A-V-SP-E-Q)
• N° accesso NCBI: NP_036872.1
• N° accesso UniProt: P07101
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pSer19)
• Informazioni sul gene: rat ... Th(25085)

Descrizione

Immunogeno

Peptide sequence around phosphorylation site of serine19 (A-V-S(p)-E-Q), according to the protein Th.

Caratteristiche e vantaggi

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Descrizione del bersaglio

The protein encoded by Tyrosine Hydroxylase is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Stato fisico

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable