SAB4300222

Anti-phospho-EIF2AK2 (pThr⁴⁴⁶) antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: Anti-EIF2AK1 antibody produced in rabbit, Anti-MGC126524 antibody produced in rabbit, Anti-PKR antibody produced in rabbit, Anti-PRKR antibody produced in rabbit, Anti-eukaryotic translation initiation factor 2-alpha kinase 2 antibody produced in rabbit
• Numero MDL: MFCD03455796
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: ~74 kDa
• Reattività contro le specie: human
• Concentrazione: 1 mg/mL
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• Isotipo: IgG
• Sequenza immunogenica: (K-R-TP-R-S)
• N° accesso NCBI: NP_001129123.1
• N° accesso UniProt: P19525
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pThr446)
• Informazioni sul gene: human ... EIF2AK2(5610)

Descrizione

Immunogeno

Peptide sequence around phosphorylation site of threonine 446 (K-R-T(p)-R-S), according to the protein EIF2AK2.

Caratteristiche e vantaggi

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Descrizione del bersaglio

Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.

Stato fisico

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable