SAB4200518

Anti-SLC1A1 antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• Sinonimo/i: Anti-EAAT3, Anti-solute carrier family 1, member 1, EAAC1
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: antigen ~70 kDa
• Reattività contro le specie: mouse, human
• Convalida avanzata: recombinant expression; Learn more about Antibody Enhanced Validation
• Concentrazione: ~1.0 mg/mL
• tecniche: immunohistochemistry: 10-20 μg/mL using formalin-fixed paraffin-embedded human small intestine.; western blot: 1.5-3.0 μg/mL using Neuro-2a cell extracts.
• N° accesso UniProt: P43005
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... SLC1A1(6505) ; mouse ... Slc1a1(20510) ; rat ... Slc1a1(25550)

Descrizione

Descrizione generale

SLC1A1 (also known as EAAC1, EAAT3) is localized at the postsynaptic site of neurons. It is expressed at moderate levels in the adult brain, mainly in the hippocampus, basal ganglia and olfactory bulb and is considered to make a minor contribution to glutamate removal from the synapse.

Immunogeno

synthetic peptide corresponding to a sequence near the C-terminus of human SLC1A1, conjugated to KLH. The corresponding sequence is identical in mouse and rat SLC1A1.

Applicazioni

Anti-SLC1A1 antibody produced in rabbit has been used in immunohistochemistry and immunoblotting.

Azioni biochim/fisiol

SLC1A1 regulates the developmental effects of glutamate. It is highly regulated by neural activity and intracellular signaling pathways involving mainly PKCa, PI3K, and glial factors, resulting in rapid changes in the trafficking of the transporter and in its membrane location.

Stato fisico

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable