SAB3501232

Anti-gp120 antibody produced in rabbit

affinity isolated antibody

• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: liquid
• Reattività contro le specie: human immunodeficiency virus 1
• Concentrazione: 1 mg/mL
• tecniche: western blot: suitable
• Isotipo: IgG
• N° accesso UniProt: Q6BBS3
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human immunodeficiency virus 1 ... env(155971)

Descrizione

Descrizione generale

gp120 Antibody: Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.

Immunogeno

gp120 antibody was raised against 16 amino acid synthetic peptide representing the major HIV-1 consensus sequence near the N-terminal region of V1/V2 loop.The immunogen is located within amino acids 80 - 130 of gp120.

Applicazioni

Gp120 antibody can be used for detection of gp120 by Western blot at 1 μg/mL.

Stato fisico

Supplied in PBS containing 0.02% sodium azide.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable