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Key Documents

SAB3500377

Anti-TRAF6 antibody produced in rabbit

Name: Anti-TRAF6 antibody produced in rabbit
Brand: SIGMA

IgG fraction of antiserum, buffered aqueous solution

Sinonimo/i:

Anti-TRAF6

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About This Item

Numero MDL:

MFCD04040629

Codice UNSPSC:

12352203

NACRES:

NA.41

Origine biologica

rabbit

Coniugato

unconjugated

Forma dell’anticorpo

IgG fraction of antiserum

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

Reattività contro le specie

human, mouse, rat

tecniche

immunocytochemistry: suitable
indirect ELISA: suitable
western blot: suitable

N° accesso NCBI

NP_004611

N° accesso UniProt

Q9Y4K3

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... TRAF6(7189)

Immunogeno

TRAF6 antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human TRAF6.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500377.

Stato fisico

Supplied in PBS with 0.02% sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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Serum amyloid A induces interleukin-33 expression through an IRF7-dependent pathway.

Lei Sun et al.

European journal of immunology, 44(7), 2153-2164 (2014-04-30)

Interleukin-33 (IL-33), an IL-1 family cytokine and nuclear alarmin, is constitutively expressed in epithelial barrier tissues and human blood vessels. However, little is known about the induced expression of IL-33 in monocytes and macrophages, which are major cytokine-producing cells of

TRAF6 is over-expressed in pancreatic cancer and promotes the tumorigenicity of pancreatic cancer cells.

Yefei Rong et al.

Medical oncology (Northwood, London, England), 31(11), 260-260 (2014-09-26)

Pancreatic cancer is one of the most lethal malignancies, with a poor response to chemotherapy and therefore it is important to identify novel therapeutic targets. TNF receptor-associated factor 6 (TRAF6) , a regulator of NF-κB signaling, has been found recently

Activation of nuclear factor kappa B in the hepatic stellate cells of mice with schistosomiasis japonica.

Xing He et al.

PloS one, 9(8), e104323-e104323 (2014-08-15)

Schistosomiasis japonica is a serious tropical parasitic disease in humans, which causes inflammation and fibrosis of the liver. Hepatic stellate cells (HSCs) are known to play an important role in schistosome-induced fibrosis, but their role in schistosome-induced inflammation is still

Brazilin selectively disrupts proximal IL-1 receptor signaling complex formation by targeting an IKK-upstream signaling components.

Juhee Jeon et al.

Biochemical pharmacology, 89(4), 515-525 (2014-04-17)

The ligation of interleukin-1 receptor (IL-1R) or tumor necrosis factor receptor 1 (TNFR1) induces the recruitment of adaptor proteins and their concomitant ubiquitination to the proximal receptor signaling complex, respectively. Such are upstream signaling events of IKK that play essential

MicroRNA-146a provides feedback regulation of lyme arthritis but not carditis during infection with Borrelia burgdorferi.

Robert B Lochhead et al.

PLoS pathogens, 10(6), e1004212-e1004212 (2014-06-27)

MicroRNAs have been shown to be important regulators of inflammatory and immune responses and are implicated in several immune disorders including systemic lupus erythematosus and rheumatoid arthritis, but their role in Lyme borreliosis remains unknown. We performed a microarray screen

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