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Documenti fondamentali

SAB1411938

ANTI-LIMCH1 antibody produced in mouse

Name: ANTI-LIMCH1 antibody produced in mouse
Brand: SIGMA

purified immunoglobulin, buffered aqueous solution

Sinonimo/i:

DKFZp434I0312, DKFZp686A01247, DKFZp686B2470, DKFZp686G18243, LIMCH1

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About This Item

Codice UNSPSC:

12352203

NACRES:

NA.41

Prodotti consigliati

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SYNA851410

Synthware^™ drying tube, 90 degree

Origine biologica

mouse

Livello qualitativo

100

Coniugato

unconjugated

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

PM

antigen 101.4 kDa

Reattività contro le specie

human

tecniche

western blot: 1 μg/mL

N° accesso NCBI

BC023546.2

N° accesso UniProt

Q9UPQ0

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... LIMCH1(22998)

Immunogeno

LIMCH1 (AAH23546.1, 1 a.a. ~ 897 a.a) full-length human protein.

Sequence
MRKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVTTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL

Azioni biochim/fisiol

LIMCH1 (LIM and calponin homology domains 1) is a multidomain protein belonging to the human mosaic domain superfamily. It is composed of calponin homology (CH) domain that acts as actin binding site and the conserved cysteine rich double Zn finger possessing Lim domain. Both the domain exist as a singlet. It has been reported that these proteins may exist in several duplex and quadruplet CH containing forms. It may be involved in the cytoskeletal and signaling pathways.

Stato fisico

Solution in phosphate buffered saline, pH 7.4

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Codice della classe di stoccaggio

10 - Combustible liquids

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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Alternative splicing for members of human mosaic domain superfamilies. I. The CH and LIM domains containing group of proteins.

Felix Friedberg

Molecular biology reports, 36(5), 1059-1081 (2008-06-17)

In this paper we examine (restricted to homo sapiens) the products resulting from gene duplication and the subsequent alternative splicing for the members of a multidomain group of proteins which possess the evolutionary conserved calponin homology CH domain, i.e. an

Duplex (or quadruplet) CH domain containing human multidomain proteins: an inventory.

Felix Friedberg

Molecular biology reports, 37(4), 1707-1716 (2009-07-01)

In this paper, the inventory presented for singlet CH (calponin homology/actin binding) domain containing human multidomain proteins is extended to several duplex and one quadruplet CH containing forms. Invariably, the duplexes are located at the begin of the molecules. The

CH domains revisited.

T Stradal et al.

FEBS letters, 431(2), 134-137 (1998-08-26)

A sequence motif of about 100 amino acids, termed the 'calponin homology domain' has been suggested to confer actin binding to a variety of cytoskeletal and signalling molecules. Here we analyse and compare the sequences of all calponin homology domain-containing

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