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Key Documents

Altri documenti

RAB0377

Sigma-Aldrich

Visfatin EIA Kit

for serum, plasma, culture supernatant and cell lysates

Sinonimo/i:

Visfatin ELISA Kit

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
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About This Item

Codice UNSPSC:
12352200
NACRES:
NA.32

Reattività contro le specie

rat, human, mouse

Confezionamento

kit of 96 wells (12 strips x 8 wells)

tecniche

ELISA: suitable
enzyme immunoassay: suitable

input

sample type serum
sample type culture supernatant(s)
sample type cell lysate
sample type plasma

assay range

inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 0.778 ng/mL
standard curve range: 0.1-1000 ng/mL

Metodo di rivelazione

colorimetric

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... NAMPT(10135)

Descrizione generale

The Visfatin Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting Visfatin peptide based on the principle of Competitive Enzyme Immunoassay.

Visfatin, also known as nicotinamide phosphoribosyltransferase (Nampt)/ pre-B Cell colony enhancing factor is encoded by the gene mapped to human chromosome 7q22.3. The gene contains 11 exons encompassing 34.7kb. The encoded protein is an adipocytokine secreted by visceral fat.

Immunogeno

Visfatin, synthetic peptide

Applicazioni

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Visfatin EIA Kit has been used to measure the concentration of visfatin in blood samples.

Azioni biochim/fisiol

Visfatin has a role in mammalian nicotinamide adenine dinucleotide (NAD+) biosynthesis. Studies have shown that mice deficient in visfatin in the forebrain excitatory neurons show hyperactivity, diminished anxiety-like behaviors and impaired learning and memory. It has also been shown that visfatin stimulates glucose uptake and adenosine monophosphate-activated protein kinase (AMPK) phosphorylation in mouse C2C12 skeletal muscle cells. Visfatin regulates inflammation and insulin sensitivity.

I componenti del kit sono disponibili anche separatamente

N° Catalogo
Descrizione
SDS
  • RABHRP3HRP-StreptavidinSDS

Pittogrammi

Corrosion
GHS05

Avvertenze

Warning

Indicazioni di pericolo

H290

Consigli di prudenza

P234 - P390

Classi di pericolo

Met. Corr. 1

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Certificati d'analisi (COA)

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Single and Concurrent Effects of Endurance and Resistance Training on Plasma Visfatin, Insulin, Glucose and Insulin Resistance of Non-Athlete Men with Obesity.
Tayebi S M, et al.
Annals of applied sport science., 4(4), 21-31 (2016)
Cahit Birdir et al.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 30(6), 629-634 (2016-04-29)
Investigating potential value of maternal serum Visfatin, sFlt-1, PlGF, AFP, PAPP-A levels at first trimester for prediction of small for gestational age (SGA) at birth. Measurements were performed in 20 SGA and 65 control cases. Logistic regression analysis adjusted for
Effects of Diet and Exercise-Induced Weight Loss in Sedentary Obese Women on Inflammatory Markers, Resistin, and Visfatin.
Khanna D, et al.
Obesity and Nutrition of J, 102 (2017)
Matthaios G Pitoulias et al.
Cytokine, 91, 140-144 (2017-01-11)
Visfatin is an adipokine molecule acting as an essential coenzyme in multiple cellular redox reactions. The increased serum levels of Visfatin have been correlated with metabolic syndrome and endothelial homeostasis. In this study we investigate the possible relationship of Visfatin
A visfatin promoter polymorphism is associated with low?grade inflammation and type 2 diabetes.
Zhang Y-Y, et al.
Obesity (Silver Spring, Md.), 14(12), 2119-2126 (2006)
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