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RAB0051

Sigma-Aldrich

Human PARC / CCL18 ELISA Kit

for serum, plasma, cell culture supernatant and urine

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About This Item

Codice UNSPSC:
41116158
NACRES:
NA.32

Reattività contro le specie

human

Confezionamento

kit of 96 wells (12 strips x 8 wells)

tecniche

ELISA: suitable
capture ELISA: suitable

input

sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type urine

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2 pg/mL
standard curve range: 2.74-2000 pg/mL

Metodo di rivelazione

colorimetric

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... CCL18(6362)

Descrizione generale

CC chemokine ligand 18 (CCL18) is expressed at high levels in human lung and serum. This CC chemokine can be found in primates only. The CCL18 gene is mapped to the human chromosome 17q11.2.
The Human PARC ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human PARC in serum, plasma, cell culture supernatants and urine.

Immunogeno

Recombinant Human PARC

Applicazioni

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Azioni biochim/fisiol

C-C motif chemokine ligand 18 (CCL18) has immunological functions and is associated with tumor progression. It is secreted by tumor associated macrophages (TAMs). The protein recruits naive T-cells and dendritic cells, and induces regulatory T-cells. It also acts as a chemokine for helper T lymphocytes and cytotoxic T lymphocytes. CCL18 has been implicated in the pathogenesis of many cancers.

Altre note

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

I componenti del kit sono disponibili anche separatamente

N° Catalogo
Descrizione
SDS

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDS

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

Pittogrammi

Corrosion

Avvertenze

Warning

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Met. Corr. 1

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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25th European Photovoltaic Solar Energy Conference and Exhibition / 5th World Conference on Photovoltaic Energy Conversion; 6-10 September 2010; Valencia; Spain; EU PVSEC Proceedings null
CCL18 from tumor-cells promotes epithelial ovarian cancer metastasis via mTOR signaling pathway
Qi Wang
Molecular Carcinogenesis (2016)
Local Concentrations of CC-Chemokine-Ligand 18 Correlate with Tumor Size in Non-small Cell Lung Cancer and Are Elevated in Lymph Node-positive Disease.
Schmid S
Anticancer Research (2016)
Shinichiro Ohshimo et al.
Respiratory medicine, 108(7), 1031-1039 (2014-05-20)
Acute exacerbation (AE) is a major cause of death in idiopathic pulmonary fibrosis (IPF). However, little is known about sensitive biomarkers for predicting AE. The aim of our study was to investigate the significance of KL-6 and CC-Chemokine Ligand 18

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