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Key Documents

PRS2301

Sigma-Aldrich

Anti-AIF antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Sinonimo/i:

Anti-Connector enhancer of kinase suppressor of Ras 1

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About This Item

Numero MDL:
MFCD02685955
Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

PM

predicted mol wt 67 kDa

Reattività contro le specie

mouse, human, rat

tecniche

immunocytochemistry: suitable
indirect ELISA: suitable
western blot: suitable

N° accesso UniProt

Q969H4

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... CNKSR1(10256)

Descrizione generale

The previously assigned protein identifier O95381 has been merged into Q969H4. Full details can be found on the UniProt database.

Immunogeno

a peptide corresponding to amino acids 593-606 of human AIF. This sequence is identical to mouse and rat AIF.

Linkage

The action of this antibody can be blocked using blocking peptide SBP2301.

Stato fisico

Solution in phosphate buffered saline containing 0.02% sodium azide

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

SBP2301

AIF Blocking Peptide for PRS2301

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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International journal of molecular sciences, 15(11), 20449-20468 (2014-11-12)
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Journal of neurochemistry, 151(6), 732-748 (2019-09-26)
NAD+ is a cofactor required for glycolysis, tricarboxylic acid cycle, and complex I enzymatic reaction. In mammalian cells, NAD+ is predominantly synthesized through the salvage pathway, where nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme. Previously, we demonstrated that NAMPT exerts
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Virology, 456-457, 205-219 (2014-06-04)
Adenovirus inundates the productively infected cell with linear, double-stranded DNA and an abundance of single-stranded DNA. The cellular response to this stimulus is antagonized by the adenoviral E1B and E4 early genes. A mutant group C adenovirus that fails to
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Archives of dermatological research, 306(10), 885-902 (2014-10-17)
TASK-3 (KCNK9 or K2P9.1) channels are thought to promote proliferation and/or survival of malignantly transformed cells, most likely by increasing their hypoxia tolerance. Based on our previous results that suggested mitochondrial expression of TASK-3 channels, we hypothesized that TASK-3 channels
Shengqiang Xu et al.
PloS one, 9(7), e100824-e100824 (2014-07-06)
Apoptosis-inducing factor (AIF) plays a crucial role in caspase-independent programmed cell death by triggering chromatin condensation and DNA fragmentation. Therefore, it might be involved in cell homeostasis and tumor development. In this study, we report significant AIF downregulation in the
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