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Key Documents

P3150

Sigma-Aldrich

Poly(Lys, Phe) 1:1 hydrobromide

mol wt 20,000-50,000

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About This Item

Numero CAS:
26700-39-0
Numero MDL:
MFCD00166387
Codice UNSPSC:
12352209
NACRES:
NA.26

Forma fisica

powder

Livello qualitativo

200

Rapporto d’alimentazione

Lys:Phe (1:1)

PM

20,000-50,000

Colore

white to off-white

applicazioni

cell analysis

Temperatura di conservazione

−20°C

Applicazioni

Poly (Lys, Phe) 1:1 hydrobromide has been used as a surfactant to bind negatively charged plasmid DNA. It has also been used to study its interaction with solvatochromic fluorescent dyes.

Risultati analitici

Molecular weight based on viscosity.

Altre note

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Helen Sjögren et al.
Biophysical chemistry, 116(1), 11-21 (2005-05-25)
The transition from alpha-helix to random coil of the titrating polyamino acid co-poly-L-(lysine, phenylalanine), (p-(Lys,Phe)), has been investigated as a function of pH and ionic strength in aqueous solution and at the air-water interface by means of circular dichroism (CD)
Tae Woo Kim et al.
International journal of pharmaceutics, 295(1-2), 35-45 (2005-04-26)
To enhance the in vitro and in vivo transfection activity of the cationic lipid emulsion (LE), three natural polycations, protamine sulfate (PS), poly-L-lysine and spermine, were selected as DNA condensing active agents. Formation of the LE/polycation/DNA ternary complexes was identified
An Environmentally Sensitive Fluorescent Dye as a Multidimensional Probe of Amyloid Formation
Emma V. Yates
The Journal of Physical Chemistry, 120 (9), 2087?2094-2087?2094 (2016)
Synthesis and properties of alternating poly(Lys-Phe) and comparison with the random copolymer poly(Lys 51, Phe 49).
G Seipke et al.
Biopolymers, 13(8), 1621-1633 (1974-01-01)
Optimising DNA binding to carbon nanotubes by non-covalent methods
Vanesa Sanz
Carbon, 49(5), 1775-1781 (2011)

Articoli

Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

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