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P2172

Sigma-Aldrich

C-Phycocyanin from Spirulina sp.

lyophilized powder

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About This Item

Numero CAS:
Numero MDL:
Codice UNSPSC:
12352202
NACRES:
NA.56

Origine biologica

Spirulina

Livello qualitativo

Forma fisica

lyophilized powder

Composizione

Protein, ~40% Lowry

Concentrazione

30-50% protein (Lowry)

Temperatura di conservazione

2-8°C

Informazioni sul gene

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Descrizione generale

C-Phycocyanin is a protein pigment, that is soluble in water. It is an important constituent of Spirulina platensis.

Applicazioni

C-Phycocyanin from Spirulina sp. has been used:
  • as a standard to characterize the fluorescence interactions and oxidation behaviors for model compounds
  • as a standard to confirm the antibacterial activity
  • to characterize the recombinantly expressed α-subunit of C-phycocyanin from Synechocystis sp. PCC6803 (HisCPC)
  • to identify the phycocyanin from water extracted Spirulina maxima sample

Azioni biochim/fisiol

C-phycocyanin, a biliprotein with antioxidant properties, was shown to induce apoptosis in HeLa cells by stimulating expression of pro-apoptotic genes as well as by inducing increased release of cytochrome c from the mitochondria.
C-phycocyanin can act as an active inhibitor of A53Tα-synuclein. It possess anti-inflammatory properties.

Confezionamento

Package size based on protein content

Stato fisico

Partially purified, contains sucrose, dithioerythritol and sodium azide as preservatives

Pittogrammi

Skull and crossbonesEnvironment

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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C-phycocyanin: a potent peroxyl radical scavenger in vivo and in vitro
Bhat VB and Madyastha KM
Biochemical and biophysical research communications, 275(1), 20-25 (2000)
C-Phycocyanin from Spirulina Inhibits ?-Synuclein and Amyloid ?-Fibril Formation but Not Amorphous Aggregation
Liu Y, et al.
Journal of Natural Products, 82(1), 66-73 (2019)
Screening of anti-bacterial activity of C-phycocyanin and its minimum inhibitory concentration (MIC) determination by agar dilution method
Murugan T and Madhavan R
Asian Journal of Biological Sciences, 6(1), 41-45 (2011)
Protective effect of water extracted Spirulina maxima on glutamate-induced neuronal cell death in mouse hippocampal HT22 cell
Lee HY, et al.
Pharmacognosy magazine, 14(54), 242-242 (2018)
Tyrosinase-catalyzed site-specific immobilization of engineered C-phycocyanin to surface
Faccio G, et al.
Scientific reports, 4(1), 5370-5370 (2014)

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