P0424

Prostaglandin F_2α tris salt

≥99%, synthetic, powder

• Sinonimo/i: (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt, PGF_2α−Tris
• Formula empirica (notazione di Hill): C₂₀H₃₄O₅ · C₄H₁₁NO₃
• Numero CAS: 38562-01-5
• Peso molecolare: 475.62
• Beilstein: 4087514
• Numero CE: 254-002-3
• Numero MDL: MFCD00077863
• Codice UNSPSC: 12352401
• eCl@ss: 42020658
• ID PubChem: 24898103
• NACRES: NA.77

Proprietà

• Origine biologica: synthetic
• Livello qualitativo: 200
• Saggio: ≥99%
• Stato: powder
• Colore: white
• Solubilità: H₂O: 1 mg/mL; ethanol: 50 mg/mL
• Gruppo funzionale: carboxylic acid; hydroxyl
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C
• Stringa SMILE: NC(CO)(CO)CO.[H][C@]1(C\C=C/CCCC(O)=O)[C@@H](O)C[C@@H](O)[C@]1([H])\C=C\[C@@H](O)CCCCC
• InChI: 1S/C20H34O5.C4H11NO3/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25;5-4(1-6,2-7)3-8/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25);6-8H,1-3,5H2/b7-4-,13-12+;/t15-,16+,17+,18-,19+;/m0./s1; IYGXEHDCSOYNKY-RZHHZEQLSA-N
• Informazioni sul gene: human ... PTGFR(5737)

Descrizione

Descrizione generale

Aqueous solutions are stable for 30 days at 2-8°C and for several months frozen at −0°C in single use aliquots. Avoid repeated freeze/thaw cycles.

Azioni biochim/fisiol

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds.

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. A positive feedback loop between endometrial PG F_2α and luteal oxytocin is responsible for completion of luteolysis.

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. Also stimulates contraction of smooth muscle, such as in bronchi, with possible involvement in asthma. This effect is at least partially mediated through tachykinin release.

Informazioni sulla sicurezza

• Pittogrammi: GHS08,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H360FD
• Consigli di prudenza: P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
• Classi di pericolo: Acute Tox. 4 Oral - Repr. 1B
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Dispositivi di protezione individuale: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges