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Documenti fondamentali

M8270

Sigma-Aldrich

Anti-Mouse IgG3 (heavy chain specific) antibody produced in goat

affinity isolated antibody, lyophilized powder

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About This Item

Numero MDL:
Codice UNSPSC:
12352203
NACRES:
NA.46

Origine biologica

goat

Livello qualitativo

200
300

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

secondary antibodies

Clone

polyclonal

Forma fisica

lyophilized powder

tecniche

Ouchterlony double diffusion: suitable

Temperatura di conservazione

2-8°C

modifica post-traduzionali bersaglio

unmodified

Descrizione generale

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections
IgG3 (heavy chain specific) antibody specifically recognizes heavy chain of mouse IgG3. Specificity of the mouse IgG3 is determined by immunodiffusion and IEP techniques. The purified antibody preparation is non-reactive with mouse IgA, IgG1, IgG2a, IgG2b, IgG3, and IgM, myeloma proteins.

Immunogeno

mouse IgG3 (myeloma protein)

Applicazioni

The purified IgG3 (heavy chain specific) antibody may be used as an immunoglobulin calibrator, reference antigen, blocking agent or coating protein in a variety of immunoassays including ELISA, dot-blot immunobinding, Western immunoblotting, immunodiffusion, immunoelectrophoresis, hemagglutination, and cell-binding assays. IgG3 (heavy chain specific) antibody was used as secondary antibody in ELISA.

Stato fisico

Lyophilized from 0.01 M sodium phosphate, 0.015 M sodium chloride, pH 7.2

Ricostituzione

Reconstitute with 0.135 M sodium chloride.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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J Pass et al.
Scandinavian journal of immunology, 58(3), 298-305 (2003-09-03)
The urokinase receptor (uPAR) is a glycolipid-anchored cell surface glycoprotein that plays a central role in extracellular proteolysis during tissue remodeling processes including cancer invasion. Furthermore, uPAR is found on the surface of both dendritic cells (DCs) and T cells
Hao Xu et al.
Oncology reports, 41(6), 3435-3443 (2019-04-20)
Glioblastoma is a lethal brain tumor type, which is frequently resistant to radiotherapy. The aim of the present study was to explore the function of legumain pseudogene 1 (LGMNP1) on radioresistance in glioblastoma. Reverse transcription‑quantitative PCR was used to detect the
Roselind S Lam et al.
Journal of immunology (Baltimore, Md. : 1950), 193(5), 2349-2362 (2014-07-30)
The role of the macrophage in the immunopathology of periodontitis has not been well defined. In this study, we show that intraoral inoculation of mice with Porphyromonas gingivalis resulted in infection, alveolar bone resorption, and a significant increase in F4/80(+)
S Hashira et al.
Pediatrics international : official journal of the Japan Pediatric Society, 42(4), 337-342 (2000-09-15)
Maternal immunoglobulin G (IgG), transferred across the placenta to the fetus during intrauterine life, is an important component of the neonatal immunological defence mechanisms against infection. There is controversy with respect to differences in placental transfer of the different IgG

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