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Documenti fondamentali

M7894

Sigma-Aldrich

IgG1, Kappa from murine myeloma

clone MOPC 21, ascites fluid, lyophilized powder

Sinonimo/i:

Mouse IgG1-κ

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About This Item

Numero MDL:
Codice UNSPSC:
12352203
NACRES:
NA.46

Origine biologica

mouse

Livello qualitativo

Coniugato

unconjugated

Forma dell’anticorpo

ascites fluid

Clone

MOPC 21, monoclonal

Stato

lyophilized powder

applicazioni

research pathology

Temperatura di conservazione

2-8°C

modifica post-traduzionali bersaglio

unmodified

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Descrizione generale

The MOPC-21 tumor line that produces mouse IgG1, κ is a mineral oil induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. Immunoglobulins G are made up of two identical light chains and two identical heavy chains, that are covalently connected by interchain disulphide bonds. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b, IgG2c and IgG3.

Applicazioni

IgG1, Kappa from murine myeloma has been used:
  • in stimulation assay and enzyme-linked immunosorbent assay (ELISA)
  • as isotype controls in islet hormone production
  • in flow cytometric analysis, in cell migration assay
  • as control antibody in evaluation of methylation

Azioni biochim/fisiol

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. It provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.

Ricostituzione

Reconstitute with 1 mL deionized water.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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