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Key Documents

M1520

Sigma-Aldrich

IgM, Kappa from murine myeloma

clone TEPC 183, ascites fluid, lyophilized powder

Sinonimo/i:

Mouse IgM-κ

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About This Item

Numero MDL:
Codice UNSPSC:
12352203
NACRES:
NA.46

Origine biologica

mouse

Livello qualitativo

Coniugato

unconjugated

Forma dell’anticorpo

ascites fluid

Clone

TEPC 183, monoclonal

Forma fisica

lyophilized powder

Temperatura di conservazione

2-8°C

modifica post-traduzionali bersaglio

unmodified

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Descrizione generale

The TEPC-183 tumor line that produces mouse IgM is a tetramethylpentadecane (pristane) induced plasmacytoma, originated and carried intraperitoneally in BALB/c mice. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. IgM is present on the surface of B lymphocytes in its monomeric form.

Applicazioni

IgM, Kappa from murine myeloma has been used as a control to study its effects on brain derived synaptic plasticity.

Azioni biochim/fisiol

IgM antibodies are present as pentamers in serum and are produced in response to antigens.

Ricostituzione

Reconstitute with 1 ml deionized water.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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The Immunoglobulins: Structure and Function (1998)
D M Reinitz et al.
Infection and immunity, 58(7), 2337-2342 (1990-07-01)
The T-cell dependency of B-cell responses to variant surface glycoprotein (VSG) epitopes exposed in their native surface conformation on Trypanosoma brucei rhodesiense clone LouTat 1 was investigated. T-cell requirements were examined by analyses of gamma globulin preparations derived from trypanosome-infected
Molecular Genetics of Immunoglobulin, 17 (1987)
A monoclonal antibody against synthetic A beta dimer assemblies neutralizes brain-derived synaptic plasticity-disrupting A beta
ONuallain B, et al.
Journal of Neurochemistry, 119(1), 189-201 (2011)
M Lohoff et al.
Infection and immunity, 56(8), 2120-2124 (1988-08-01)
The well-established polyclonal B-cell stimulation in the lymphoid organs in mice infected with Leishmania major is thought to be dependent on T cells. Here we present clear experimental evidence that this is indeed the case by showing that BALB/c-derived, L3T4-positive

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