L5412
Anti-Lymphotoxin β Receptor antibody produced in goat
affinity isolated antibody, lyophilized powder
Sinonimo/i:
Anti-LT-βR
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About This Item
Prodotti consigliati
Origine biologica
goat
Livello qualitativo
Coniugato
unconjugated
Forma dell’anticorpo
affinity isolated antibody
Tipo di anticorpo
primary antibodies
Clone
polyclonal
Stato
lyophilized powder
Reattività contro le specie
human
tecniche
flow cytometry: 2.5 μg using 106 cells
western blot: 0.1-0.2 μg/mL
N° accesso UniProt
Temperatura di conservazione
−20°C
Informazioni sul gene
human ... LTBR(4055)
Descrizione generale
The antibody will recognize recombinant human LT-βR. Applications include in immunoblotting, flow cytometry, and agonist activity.
Immunogeno
recombinant human lymphotoxin β receptor extracellular domain expressed in NS0 cells.
Azioni biochim/fisiol
Lymphotoxins (LT) alpha and beta are homologs of tumor necrosis factor. These cytokines play important role in the development and function of immune system, immune response and autoimmunity. The signaling mediated by LTβ receptor mediates autoimmune reactions and the development of secondary lymphoid organs.
Stato fisico
Lyophilized from 0.2 μm filtered solution of phosphate buffered saline containing carbohydrates.
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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Arthritis research, 4 Suppl 3, S141-S152 (2002-07-12)
Tumor necrosis factor (TNF)-alpha and lymphotoxin (LT) alpha/beta play multiple roles in the development and function of the immune system. This article focuses on three important aspects of the effects of these cytokines on the immune response and on autoimmunity.
Role of lymphotoxin in experimental models of infectious diseases: potential benefits and risks of a therapeutic inhibition of the lymphotoxin-beta receptor pathway.
Infection and immunity, 73(11), 7077-7088 (2005-10-22)
Immunology and cell biology, 74(5), 465-472 (1996-10-01)
Tumour necrosis factor (TNF) is a highly potent, proinflammatory cytokine with broad-ranging functions from the regulation of endothelial cell adhesion molecules to facilitate entry of leucocytes into tissues, to direct induction of cellular cytotoxicity. This diversity of function potentially attributable
PloS one, 9(12), e114791-e114791 (2014-12-17)
Asthma-related mortality has been decreasing due to inhaled corticosteroid use, but severe asthma remains a major clinical problem. One characteristic of severe asthma is resistance to steroid therapy, which is related to neutrophilic inflammation. Recently, the tumor necrosis factor superfamily
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