I1020

Interleukin-4 from mouse

IL-4, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• Sinonimo/i: mIL-4, Interleukin-4 human
• Numero MDL: MFCD00166698
• Codice UNSPSC: 12352202
• NACRES: NA.77

Proprietà

• Origine biologica: mouse
• Ricombinante: expressed in E. coli
• Saggio: ≥98% (SDS-PAGE)
• Forma fisica: lyophilized powder
• Potenza: 0.1-2.0 ng/mL ED₅₀/EC₅₀
• Qualità: endotoxin tested
• PM: ~13.5 kDa
• Confezionamento: pkg of 5 μg
• tecniche: cell culture | mammalian: suitable
• Impurezze: <0.1 EU/μg
• N° accesso UniProt: P07750
• Temperatura di conservazione: −20°C
• Informazioni sul gene: mouse ... Il4(16189)

Descrizione

Applicazioni

Interleukin-4 from mouse has been used:

• as a component of cell culture media for class switch recombination assay
• to study its therapeutic benefits for mucosal healing
• as a pioglitazone or new peroxisome proliferator-activated receptor agonist (GQ-11)

Azioni biochim/fisiol

Interleukin-4 (IL-4) is a lymphokine with profound effects on the growth and differentiation of immunologically competent cells. IL-4 is also known as B cell stimulatory factor-1 (BSF-1), T cell growth factor-2 (TCGF-2) and mast-cell growth factor-2 (MCGF-2). Inhibits VEGF-induced and FGF-Basic-induced angiogenesis. IL-4 is a complex glycoprotein released by a subset of activated T cells. Treatment of IL-4 with specific glycosidases yields an active polypeptide. Human and mouse IL-4 share 50% amino acid sequence homology, but their biological actions are species-specific.

Stato fisico

Lyophilized, 0.2 μm filtered, with no additives.

Risultati analitici

The proliferative activity is tested in culture using mouse HT-2 cells.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)