G7504
Guanosine 3′,5′-cyclic monophosphate
≥98% (HPLC), powder, intracellular mediator
Sinonimo/i:
cGMP, cyclic GMP
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About This Item
Formula empirica (notazione di Hill):
C10H12N5O7P
Numero CAS:
Peso molecolare:
345.21
Numero CE:
Numero MDL:
Codice UNSPSC:
41106305
ID PubChem:
NACRES:
NA.77
Prodotti consigliati
Nome del prodotto
Guanosine 3′,5′-cyclic monophosphate, ≥98% (HPLC), powder
Livello qualitativo
Saggio
≥98% (HPLC)
Stato
powder
Colore
white
Solubilità
0.2 M NaHCO3: 50 mg/mL
Temperatura di conservazione
−20°C
Stringa SMILE
NC1=NC(=O)c2ncn(C3OC4COP(O)(=O)OC4C3O)c2N1
InChI
1S/C10H12N5O7P/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17)
ZOOGRGPOEVQQDX-UHFFFAOYSA-N
Azioni biochim/fisiol
An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).
Caratteristiche e vantaggi
This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox and Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organi bersaglio
Respiratory system
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Dispositivi di protezione individuale
dust mask type N95 (US), Eyeshields, Gloves
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