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F5259

Sigma-Aldrich

Anti-Human IgA (α-chain specific)−FITC antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Sinonimo/i:

Goat Anti-Human IgA (α-chain specific)−Fluorescein isothiocyanate

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About This Item

Numero MDL:
MFCD00162415
Codice UNSPSC:
12352203
NACRES:
NA.46

Origine biologica

goat

Livello qualitativo

200

Coniugato

FITC conjugate

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

secondary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

tecniche

direct immunofluorescence: 1:16

Temperatura di conservazione

2-8°C

modifica post-traduzionali bersaglio

unmodified

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Descrizione generale

IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces
Anti-Human IgA (α-chain specific)-FITC antibody is specific for α chain of human IgA. Goat Anti-Human IgA is conjugated to Fluorescein Isothiocyanate (FITC), Isomer I.

Immunogeno

Purified human IgA

Applicazioni

Anti-Human IgA (α-chain specific)-FITC antibody may be used for direct immunofluorescence at a working antibody dilution of 1:16 to 1:32. A dilution of 1:100 was used for immunohistochemistry of cryosections of human sural nerves.

Stato fisico

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 1% BSA and 15 mM sodium azide

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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G B Rosoklija et al.
Acta neuropathologica, 99(1), 55-62 (2000-01-29)
Quantitative immunocytochemical analysis of complement proteins (CP) was performed on sural nerve biopsies from 15 patients with diabetic neuropathy (DN) and 18 nondiabetic patients with other forms of chronic neuropathy (ON). The mean age of the patients and the pathological
Helia N Sanchez et al.
Nature communications, 11(1), 60-60 (2020-01-04)
Short-chain fatty acids (SCFAs) butyrate and propionate are metabolites from dietary fiber's fermentation by gut microbiota that can affect differentiation or functions of T cells, macrophages and dendritic cells. We show here that at low doses these SCFAs directly impact B
Clayton A White et al.
Journal of immunology (Baltimore, Md. : 1950), 193(12), 5933-5950 (2014-11-14)
Class-switch DNA recombination (CSR) and somatic hypermutation (SHM), which require activation-induced cytidine deaminase (AID), and plasma cell differentiation, which requires B lymphocyte-induced maturation protein-1 (Blimp-1), are critical for the generation of class-switched and hypermutated (mature) Ab and autoantibody responses. We
Valeria R Villella et al.
The EMBO journal, 38(2) (2018-12-01)
Intestinal handling of dietary proteins usually prevents local inflammatory and immune responses and promotes oral tolerance. However, in ~ 1% of the world population, gluten proteins from wheat and related cereals trigger an HLA DQ2/8-restricted TH1 immune and antibody response leading
Matthew Paul et al.
mAbs, 6(6), 1585-1597 (2014-12-09)
Recombinant Secretory IgA (SIgA) complexes have the potential to improve antibody-based passive immunotherapeutic approaches to combat many mucosal pathogens. In this report, we describe the expression, purification and characterization of a human SIgA format of the broadly neutralizing anti-HIV monoclonal
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Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

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