E8515

β-Estradiol 3-benzoate

≥97%

• Sinonimo/i: 1,3,5(10)-Estratriene-3,17β-diol 3-benzoate, 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-benzoate, 3-Benzoyloxy-17β-estrol
• Formula empirica (notazione di Hill): C₂₅H₂₈O₃
• Numero CAS: 50-50-0
• Peso molecolare: 376.49
• Beilstein: 3107526
• Numero CE: 200-043-7
• Numero MDL: MFCD00003692
• Codice UNSPSC: 51111800
• ID PubChem: 24894677
• NACRES: NA.77

Proprietà

• Livello qualitativo: 200
• Saggio: ≥97%
• Punto di fusione: 191-198 °C (lit.)
• Stringa SMILE: [H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])CCc4cc(OC(=O)c5ccccc5)ccc24
• InChI: 1S/C25H28O3/c1-25-14-13-20-19-10-8-18(28-24(27)16-5-3-2-4-6-16)15-17(19)7-9-21(20)22(25)11-12-23(25)26/h2-6,8,10,15,20-23,26H,7,9,11-14H2,1H3/t20-,21-,22+,23+,25+/m1/s1; UYIFTLBWAOGQBI-BZDYCCQFSA-N

Descrizione

Applicazioni

β-Estradiol 3-benzoate has been used:to mimic estradiol in rat during the oestrous cycle in rats. It has also been used along with progesterone for the induction of sexual receptivity in female rat.

Used in a study of general steroid metabolism and clearing, as groundwork for anabolic steroid screening in athletes.

Azioni biochim/fisiol

β-Estradiol 3-benzoate is a synthetic estrogen. It favors breast cancer progression. It is an endocrine disrupting chemicals. It interacts with endocrine system and cause harmful effect on reproduction in animals and humans. It binds to estrogen receptors and favors tumor metastatis in breast, prostate and bone cells.

Informazioni sulla sicurezza

• Pittogrammi: GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H351,H360FD
• Consigli di prudenza: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classi di pericolo: Carc. 2 - Repr. 1B
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Dispositivi di protezione individuale: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges