MOR/CPR

96042333, human lung, Not specified

• Codice UNSPSC: 41106514

Proprietà

• Nome del prodotto: MOR/CPR, 96042333
• Origine biologica: human lung
• Modalità di accrescimento: Aggregates in suspension
• Cariotipo: Not specified
• Morfologia: Not specified
• Prodotti: Not specified
• Recettori: Not specified
• tecniche: cell culture | mammalian: suitable
• Malattie correlate: cancer
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −196°C

Descrizione

Origine della linea cellulare

Human lung adenocarcinoma, drug-resistant

Descrizione della linea cellulare

MOR/CPR has been developed by growing the parent line, MOR, in increasing concentrations of cisplatin. The cells are cross-resistant to melphalan but show little or no cross-resistance to other platinum compounds. Cisplatin accumulation has been found to be reduced compared to the parent line.

Applicazioni

Analysis of acquired drug resistance

Terreno di coltura

RPMI 1640 + 2mM Glutamine + 1μg/ml cisplatin + 10% Foetal Bovine Serum (FBS).

Mantenimento delle subcolture

Split subconfluent cultures (70-80%) 1:2 to 1:4 seeding at 2-4 x 10,000 cells/cm² using 0.25% trypsin or trypsin/EDTA; 5% CO₂; 37°C. It is recommended to culture the cells without drug after resuscitation until the first passage. These cells produce a

Altre note

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