C6737
Chondroitin sulfate sodium salt from bovine cartilage
98-102% (CPC, titration)
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About This Item
Prodotti consigliati
Origine biologica
bovine cartilage
Livello qualitativo
Grado
standard (for CPC (cetylpyridinium chloride) titration)
Saggio
98-102% (CPC, titration)
Forma fisica
powder
Attività ottica
[α]20/D -30 to -20 °, c = 5% (w/v) in water
Impurezze
<10.0% water (Karl Fischer)
Colore
white to off-white
Solubilità
H2O: soluble 50 mg/mL, clear to hazy, colorless to faintly yellow
Cationi in tracce
Na: 7.4-8.8% (anhydrous)
Temperatura di conservazione
2-8°C
Stringa SMILE
[Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]2O[C@@H]([C@H](O)[C@@H](O)[C@@H]2O)C(O)=O
Descrizione generale
Chondroitin, a glucosaminoglycan (GAG), is a polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) that can be sulfated on the either or both GalNAc and GlcA units. Chondroitin and its sulfates are frequently attached to proteins to form proteoglycans.
Applicazioni
Chondroitin sulfate, a glucosaminoglycan (GAG) polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA), is used in a wide variety of areas of research including bioengineering. Chondroitin sulfate may be used as a biomaterial copolymer or surface derivatization reagent in the development of drug delivery vehicles, tissue engineering devices and bioscaffolds. Chondroitin sulfate may be used for the development of biocompatible structures such as hydrogels, sponges, biofilms, microspheres and micelles.
Azioni biochim/fisiol
As a large, negatively charged, hydrophilic molecule that is too inflexible to fold into a compact globular structure, chondroitin sulfate molecules form porous hydrated gels, providing mechanical support to tissue and allowing rapid diffusion of water-soluble molecules and migration of cells.
Componenti
Chondroitin is an acidic mucopolysaccharide found in cartilage, skin, cornea, and umbilical cord. It is composed of alternating N-acetylgalactosamine, D-glucuronic acid, and sulfate residues in equimolar quantities that can be sulfated on either of its subunits. Sulfation can occur at the 6 and/or 4-position of the galactosamine moiety, with potential for any individual disaccharide unit to be 6-sulfated, 4-sulfated, 4,6-disulfated, or unsulfated.
Avvertenza
Store this product at 2-8°C.
Nota sulla preparazione
This product is soluble in water at 100 mg/mL.
Altre note
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Codice della classe di stoccaggio
13 - Non Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
Certificati d'analisi (COA)
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I clienti hanno visto anche
Zhongming Liang et al.
Journal of pharmaceutical and biomedical analysis, 28(2), 245-249 (2002-04-04)
A photometric titration method was developed and validated to quantitate sodium chondroitin sulfate in raw materials and Cosequin DS chewable tablet(1). About 0.1% (w/v) cetylpyridinium chloride was used to titrate sodium chondroitin sulfate with photometric indication at wavelength 420 nm.
Satoshi Uchida et al.
Journal of controlled release : official journal of the Controlled Release Society, 155(2), 296-302 (2011-05-17)
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Feng Wang et al.
Acta biomaterialia, 6(6), 1978-1991 (2009-12-17)
A family of injectable, rapid gelling and highly flexible hydrogel composites capable of releasing insulin-like growth factor (IGF-1) and delivering mesenchymal stromal cell (MSC) were developed. Hydrogel composites were fabricated from Type I collagen, chondroitin sulfate (CS) and a thermosensitive
Yu-Lun Lo et al.
Advanced healthcare materials, 2(11), 1458-1468 (2013-04-26)
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Determination of the chondroitin sulfate disaccharides in dog and horse plasma by HPLC using chondroitinase digestion, precolumn derivatization, and fluorescence detection.
Du J, Eddington N.
Analytical Biochemistry, 306, 252-258 (202)
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