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94259

Sigma-Aldrich

(±)-Mevalonic acid 5-pyrophosphate tetralithium salt

≥80% (qNMR)

Sinonimo/i:

(±)-MVAPP, (±)-Mevalonic acid 5-diphosphate tetralithium salt

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About This Item

Formula empirica (notazione di Hill):
C6H10Li4O10P2
Numero CAS:
108869-00-7
Peso molecolare:
331.85
Numero MDL:
MFCD16875404
Codice UNSPSC:
12352201
ID PubChem:
329770318
NACRES:
NA.25

Saggio

≥80% (qNMR)

Forma fisica

powder

Colore

white

Temperatura di conservazione

−20°C

Stringa SMILE

[Li+].[Li+].[Li+].[Li+].CC(O)(CCOP([O-])(=O)OP([O-])([O-])=O)CC([O-])=O

InChI

1S/C6H14O10P2.4Li/c1-6(9,4-5(7)8)2-3-15-18(13,14)16-17(10,11)12;;;;/h9H,2-4H2,1H3,(H,7,8)(H,13,14)(H2,10,11,12);;;;/q;4*+1/p-4
GFIXUUFXTAPBAD-UHFFFAOYSA-J

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Azioni biochim/fisiol

Metabolite of the mevalonate pathway, which plays a key role in the biosynthesis of sterols, dolichol, heme and ubiquinone. Of interest for research in the disease areas oncology, autoimmune diseases, artherosclerosis and Alzheimer disease, as well as for inherited deficiencies of mevalonate kinase. Mevalonic acid 5-pyrophosphate was shown to elevate ubiquinone levels in rat liver tissues.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Altre note

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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Procedures for the isolation and analysis of all 11 intermediates of the mevalonic acid pathway from acetyl-CoA through geranylgeranyl pyrophosphate were developed. Both acid-labile and base-labile metabolites are simultaneously extracted with good recoveries into 7 M urea at neutral pH
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