905H-0

Cytokeratin 5 (EP1601Y) + Cytokeratin 14 (LL002)

Mouse and Rabbit MonoclonalAntibody

• Sinonimo/i: Cytokeratin 5 (EP1601Y) + Cytokeratin 14 (LL002) Mouse and Rabbit Monoclonal Antibody
• Codice UNSPSC: 12352200
• NACRES: NA.41

Proprietà

• Origine biologica: mouse; rabbit
• Livello qualitativo: 100; 500
• Coniugato: unconjugated
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: EP1601Y + LL002, monoclonal
• Descrizione: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Forma fisica: buffered aqueous solution
• Reattività contro le specie: human
• Confezionamento: bottle of 1.0 mL predilute (905H-07); bottle of 7.0 mL predilute (905H-08)
• Produttore/marchio commerciale: Cell Marque^™
• Concentrazione: 0.1-1.5 μg/mL (predilute)
• Isotipo: IgG3; IgG
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• Informazioni sul gene: human ... KRT5(3852)

Descrizione

Descrizione generale

Cytokeratin 5 is an intermediate filament protein of 58 kD molecular wt. amongst the cytokeratin family. It is a type II (basic) cytokeratin. Antibodies to this protein identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium. Cytokeratin 14 is a 50 kD polypeptide found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-Cytokeratin 5 has been useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelial mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas immunostain with CK5. Anti-CK14 has been demonstrated to be useful in differentiating squamous cell carcinomas from other epithelial tumors. Anti-CK5, along with anti-CK14, has found application in identifying the basaloid phenotype of breast carcinoma, a tumor with poor prognosis.

Qualità

IVD

IVD

IVD

RUO

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

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Altre note

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