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53163

Sigma-Aldrich

Hyaluronic acid sodium salt from Streptococcus equi

mol wt 750,000-1,000,000

Sinonimo/i:

Sodium hyaluronate

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About This Item

Numero CAS:
Numero MDL:
Codice UNSPSC:
12352201
NACRES:
NA.25

Origine biologica

(Streptococcus equi)

Livello qualitativo

Forma fisica

powder

PM

750,000-1,000,000

Colore

white

Solubilità

water: ~5 g/L

Compatibilità

conforms to structure for Infrared spectrum

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

InChI

1S/C28H44N2O23.Na/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43;/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45);/q;+1/t7-,8-,9-,10-,11-,12-,13+,14+,15-,16-,17-,18-,19-,20+,21+,22+,25-,26+,27-,28-;/m1./s1
YWIVKILSMZOHHF-QJZPQSOGSA-N

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Applicazioni

suitable as substrate for hyaluronidase

Altre note

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Dianhua Jiang et al.
Physiological reviews, 91(1), 221-264 (2011-01-21)
Accumulation and turnover of extracellular matrix components are the hallmarks of tissue injury. Fragmented hyaluronan stimulates the expression of inflammatory genes by a variety of immune cells at the injury site. Hyaluronan binds to a number of cell surface proteins
H Porsch et al.
Oncogene, 32(37), 4355-4365 (2012-10-31)
Epithelial-mesenchymal transition (EMT) is a developmental program, which can be adopted by cancer cells to increase their migration and ability to form metastases. Transforming growth factor β (TGFβ) is a well-studied inducer of EMT. We demonstrate that TGFβ potently stimulates
Melissa R Junttila et al.
Nature, 501(7467), 346-354 (2013-09-21)
Tumour formation involves the co-evolution of neoplastic cells together with extracellular matrix, tumour vasculature and immune cells. Successful outgrowth of tumours and eventual metastasis is not determined solely by genetic alterations in tumour cells, but also by the fitness advantage
J Ye et al.
Eye (London, England), 26(7), 1012-1020 (2012-05-19)
To investigate the toxic effects of ethylenediaminetetraacetic acid disodium salt (EDTA), a corneal penetration enhancer in topical ophthalmic formulations, on DNA in human corneal epithelial cells (HCEs), and to investigate whether the effect induced by EDTA can be inhibited by
Xiao Tian et al.
Nature, 499(7458), 346-349 (2013-06-21)
The naked mole rat (Heterocephalus glaber) displays exceptional longevity, with a maximum lifespan exceeding 30 years. This is the longest reported lifespan for a rodent species and is especially striking considering the small body mass of the naked mole rat. In

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