482R-1

p63 (EP174) Rabbit Monoclonal Primary Antibody

• Codice UNSPSC: 12352203

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100; 500
• Coniugato: unconjugated
• Forma dell’anticorpo: culture supernatant
• Tipo di anticorpo: primary antibodies
• Clone: EP174
• Descrizione: For In Vitro Diagnostic Use in Select Regions
• Forma fisica: buffered aqueous solution
• Reattività contro le specie: human
• Confezionamento: vial of 0.1 mL concentrate (482R-14); vial of 0.1 mL concentrate, Research Use Only (482R-14-RUO); vial of 0.5 mL concentrate (482R-15); vial of 1.0 mL concentrate (482R-16); vial of 1.0 mL concentrate, Research Use Only (482R-16-RUO); vial of 1.0 mL pre-dilute ready-to-use, Research Use Only (482R-17-RUO); vial of 1.0 mL pre-dilute, ready to use (482R-17); vial of 25.0 mL pre-dilute ready-to-use (482R-10); vial of 25.0 mL pre-dilute ready-to-use, Research Use Only (482R-10-RUO); vial of 7.0 mL pre-dilute, ready to use (482R-18); vial of 7.0 mL pre-dilute, ready to use, Research Use Only (482R-18-RUO)
• Produttore/marchio commerciale: Cell Marque
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable (1:100-1:200 (concentrated))
• Isotipo: IgG
• Controllo: lung (squamous cell carcinoma), prostate
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• Visualizzazione: nuclear

Descrizione

Descrizione generale

p63 is a transcription factor that regulates many cell activities, including cell proliferation, maintenance, differentiation, adhesion, and apoptosis.¹ It has been found to be a sensitive and specific marker of myoepithelial and basal cell populations in prostate, breast, skin, and salivary gland. Additionally, p63 has also demonstrated immunohistochemical utility in identifying benign and malignant breast lesions.² In prostatic carcinomas, it can also be used to recognize benign glands adjacent to malignant glands.³ p63 can also be used to differentiate adenocarcinoma of the lungs, where it is usually negative, from squamous cell carcinoma, which can be useful for advanced stages of the carcinoma where surgery is no longer an option.⁴

Qualità

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota sulla preparazione

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Altre note

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Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2