426R-1

STAT6 (EP325) Rabbit Monoclonal Primary Antibody

• Sinonimo/i: Signal Transducer and Activator of Transcription
• Codice UNSPSC: 12352203

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100; 500
• Coniugato: unconjugated
• Forma dell’anticorpo: culture supernatant
• Tipo di anticorpo: primary antibodies
• Clone: EP325, monoclonal
• Descrizione: For In Vitro Diagnostic Use in Select Regions
• Forma fisica: buffered aqueous solution
• Reattività contro le specie: human
• Confezionamento: vial of 0.1 mL concentrate (426R-14); vial of 0.1 mL concentrate Research Use Only (426R-14-RUO); vial of 0.5 mL concentrate (426R-15); vial of 1.0 mL concentrate (426R-16); vial of 1.0 mL concentrate Research Use Only (426R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (426R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (426R-17); vial of 7.0 mL pre-dilute ready-to-use (426R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (426R-18-RUO)
• Produttore/marchio commerciale: Cell Marque^™
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• Isotipo: IgG
• Controllo: solitary fibrous tumor
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• Visualizzazione: nuclear
• Informazioni sul gene: human ... STAT6(6778)

Descrizione

Descrizione generale

STAT6, a member of the signal transducers and activators of transcription (STAT) family, has been found to form recurrent fusions with NAB2 on chromosome 12q13 in the majority of solitary fibrous tumors. Inactivated STAT6 can be found in the form of a dimer located in the cytoplasm. STAT6 and NAB2 fusion enables cytosolic STAT6 to migrate to the nucleus and thus allowing for detection in immunohistochemical assays. NAB2-STAT6 fusion transcriptions have been reported in the majority of solitary fibrous tumors but not in meningiomas, hemangioblastomas, schwannomas, and hemangiomas. This makes STAT6 a useful marker in distinguishing solitary fibrous tumors from other morphologically similar tumors.

Qualità

IVD

IVD

IVD

RUO

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota sulla preparazione

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Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable