Passa al contenuto
Merck
Tutte le immagini(1)

Key Documents

17772

Sigma-Aldrich

Retinolo

≥95.0% (HPLC), ~2700 U/mg

Sinonimo/i:

tutto trans-3,7-dimetil-9-(2,6,6-trimetil-1-cicloesen-1-il)-2,4,6,8-nonatetraen-1-olo, Alcol della vitamina A, Axeroftolo, Vitamina A, Vitamina A1

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Formula empirica (notazione di Hill):
C20H30O
Numero CAS:
Peso molecolare:
286.45
Beilstein:
403040
Numero CE:
Numero MDL:
Codice UNSPSC:
12352205
eCl@ss:
34058018
ID PubChem:
NACRES:
NA.79

Origine biologica

synthetic

Livello qualitativo

Saggio

≥95.0% (HPLC)

Forma fisica

(Powder or Crystal with Lumps)

Attività specifica

~2700 U/mg

Colore

yellow to dark yellow

Punto di fusione

61-63 °C (lit.)

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO)=C(C)CCC1

InChI

1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
FPIPGXGPPPQFEQ-OVSJKPMPSA-N

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinol is biologically active in a wide range of processes.
Retinol or all-trans-retinol is a 20-carbon molecule with cyclohexenyl ring, a side chain with four double bonds (all in trans configuration) and an alcohol end group.

Applicazioni

Retinol has been used as a standard in ultra-performance liquid chromatography - tandem mass spectrometer (UPLC-MS/MS) for the vitamins detection and quantification.

Azioni biochim/fisiol

Retinol and its derivatives exhibit anti-aging properties. Retinol is used for treating wrinkles and signs of aging. However, due to its photo instability and skin irritation potency, it is hardly used in cosmetic formulations. Retinol is also used as a therapeutic for dermatoses. Its deficiency leads to xerosis and follicular hyperkeratosis.

Definizione di unità

1 U corresponds to 1 international U acc. to Ph Eur II, 217 (1983)

Pittogrammi

Health hazardExclamation mark

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Aquatic Chronic 4 - Eye Irrit. 2 - Repr. 1B - Skin Sens. 1

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 1

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 6

1 of 6

Retinyl acetate United States Pharmacopeia (USP) Reference Standard, solution of retinyl acetate (vitamin A) in peanut oil

USP

1716002

Retinyl acetate

vibrant-m

R0290000

Retinol esters

9-cis-Retinal vitamin A analog

Sigma-Aldrich

R5754

9-cis-Retinal

Retinyl palmitate United States Pharmacopeia (USP) Reference Standard

USP

1602502

Retinyl palmitate

Retinil acetato Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1236

Retinil acetato

Effects of dietary lead exposure on vitamin levels in great tit nestlings-An experimental manipulation
Ruiz S, et al.
Environmental Pollution (Barking, Essex : 1987), 213(2), 688-697 (2016)
N M Hamdan et al.
Journal of dental research, 92(12 Suppl), 146S-153S (2013-10-26)
People wearing mandibular two-implant overdentures (IOD) chew food with less difficulty than those wearing conventional complete dentures (CD). However, there is still controversy over whether or not this results in better dietary intake. In this randomized clinical trials (RCT), the
Jacqueline A Jumpsen et al.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 5(2), 77-84 (2006-03-02)
The objective of this study was to investigate the effect of docosahexaenoic acid (DHA) supplementation on blood and intestinal DHA levels and lung function in mild/moderately affected adult CF patients with the DeltaF508 genotype. Cystic Fibrosis (CF) patients often present
Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety
Mukherjee S, et al.
Clinical Interventions in Aging, 1(4), 327-327 (2006)
K R Norum et al.
The American journal of clinical nutrition, 56(4), 735-744 (1992-10-01)
We discuss vitamin A with emphasis on its absorption, transport, cellular uptake, storage, and intracellular metabolism. Dietary retinyl esters are hydrolyzed to retinol in the intestinal lumen before absorption by enterocytes. Carotenoids are absorbed and then partially converted to retinol

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.