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16005

Sigma-Aldrich

Brij® L23

main component: tricosaethylene glycol dodecyl ether

Sinonimo/i:

Brij 35, C12E23, Polyoxyethylene (23) lauryl ether

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About This Item

Numero CAS:
9002-92-0
Numero MDL:
MFCD00080891
Codice UNSPSC:
12161900
ID PubChem:
57647536
NACRES:
NA.21

Livello qualitativo

200

Descrizione

non-ionic

Stato

pellets

CMC

91 μM

Punto di fusione

39-43 °C

HLB

16.9

Solubilità

H2O: 40 mg/mL at 20 °C, clear to slightly hazy, colorless

Cationi in tracce

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤500 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤500 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

Gruppo funzionale

ether
hydroxyl

Stringa SMILE

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C58H118O24/c1-2-3-4-5-6-7-8-9-10-11-13-60-15-17-62-19-21-64-23-25-66-27-29-68-31-33-70-35-37-72-39-41-74-43-45-76-47-49-78-51-53-80-55-57-82-58-56-81-54-52-79-50-48-77-46-44-75-42-40-73-38-36-71-34-32-69-30-28-67-26-24-65-22-20-63-18-16-61-14-12-59/h59H,2-58H2,1H3
IEQAICDLOKRSRL-UHFFFAOYSA-N

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Applicazioni

Brij®L23 is a detergent used for measuring the concentration of carbon black in lung tissues. It has also been used for selective and rapid solubilization of microbial membrane aldehyde dehydrogenase. Additionally, the product has also been used for assessing whether acrolein could lead to pro-enzyme activation by using gelatin zymography.

Azioni biochim/fisiol

Brij® L23 also referred to as Brij 35 or Polyoxyethylene (23) lauryl ether is a non-ionic detergent that lowers the non-specific protein adsorption and reduces electroosmotic pumping drastically. This allows the pH to be varied without adversely affecting the flow rate. It also used as a nonionic surfactant that decreases the absorbance of the blank, inhibits turbidity as well as provides linearity.

Altre note

Non-ionic polyoxyethylene ether. Used for selective and rapid solubilization of microbial membrane aldehyde dehydrogenase.

Note legali

Brij is a registered trademark of Croda International PLC

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

>300.2 °F - closed cup

Punto d’infiammabilità (°C)

> 149 °C - closed cup

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
BCCG6913
BCCG3255
BCCF4749
BCCC7660
BCCC0397

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Lingling Chen et al.
Scientific reports, 7(1), 12218-12218 (2017-09-25)
Optical clearing methods can facilitate deep optical imaging in biological tissue by reducing light scattering and this has enabled accurate three-dimensional signal visualization and quantification of complex biological structures. Unfortunately, existing optical clearing approaches present a compromise between maximizing clearing
R Hommel et al.
Journal of basic microbiology, 30(4), 297-300 (1990-01-01)
An improved solubilization procedure for the membrane-bound quinoprotein aldehyde dehydrogenase from Acetobacter rancens CCM 1774 was established. After the first solubilization of membrane enzymes by Brij 35 which provided important extraction of membrane proteins other than aldehyde dehydrogenase, the application
J K Towns et al.
Analytical chemistry, 63(11), 1126-1132 (1991-06-01)
Capillary zone electrophoretic separations of proteins have been achieved by using nonionic surfactant coated capillaries. Capillaries were prepared by derivatization of the silica surface with octadecylsilane followed by the deposition of a layer of nonionic surfactant from an aqueous solution
B T Dumas et al.
Clinica chimica acta; international journal of clinical chemistry, 258(1), 21-30 (1997-02-03)
A rapid and reliable method for measuring serum albumin employing bromcresol green is described. The addition of albumin to a solution of bromcresol green in a 0.075 M succinate buffer pH 4.20 results in an increase in absorbance at 628
Hitesh S Deshmukh et al.
American journal of respiratory cell and molecular biology, 38(4), 446-454 (2007-11-17)
Chronic obstructive pulmonary disease (COPD), a global public health problem, is characterized by progressive difficulty in breathing, with increased mucin production, especially in the small airways. Acrolein, a constituent of cigarette smoke and an endogenous mediator of oxidative stress, increases
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