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Documenti fondamentali

108M-9

Sigma-Aldrich

CD8 (C8/144B) Mouse Monoclonal Antibody

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100
500

Coniugato

unconjugated

Forma dell’anticorpo

diluted ascites fluid

Tipo di anticorpo

primary antibodies

Clone

C8/144B, monoclonal

Descrizione

For In Vitro Diagnostic Use in Select Regions (See Chart)

Stato

buffered aqueous solution

Reattività contro le specie

human

Confezionamento

vial of 0.1 mL concentrate (108M-94)
vial of 0.5 mL concentrate (108M-95)
bottle of 1.0 mL predilute (108M-97)
vial of 1.0 mL concentrate (108M-96)
bottle of 7.0 mL predilute (108M-98)

Produttore/marchio commerciale

Cell Marque®

tecniche

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

Isotipo

IgG1κ

Controllo

tonsil

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Visualizzazione

membranous

Informazioni sul gene

human ... CD8A(925)

Categorie correlate

Descrizione generale

Anti-CD8 is a T cell marker for the detection of cytotoxic/suppresser cells of blood lymphocytes. CD8 is also detected on NK cells, most thymocytes, a subpopulation of null cells and bone marrow cells. This antibody, along with other markers, can be used to distinguish between reactive and neoplastic T-cells.

Qualità


IVD

IVD

IVD

RUO

Linkage

CD8 Positive Control Slides, Product No. 108S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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M L Rossi et al.
Journal of clinical pathology, 41(3), 314-319 (1988-03-01)
Twenty four meningiomas (17 benign and seven "atypical" were reacted with a panel of monoclonal antibodies to macrophages, lymphocytes, and HLA DR antigens. All the tumours contained macrophages but these cells were more numerous in the atypical meningiomas. Lymphocytes, almost
Immunohistological analysis of human lymphoma: correlation of histological and immunological categories.
H Stein et al.
Advances in cancer research, 42, 67-147 (1984-01-01)
F Phan-Dinh-Tuy et al.
Molecular immunology, 19(12), 1649-1654 (1982-12-01)
Three human lymphocyte differentiation antigens, specific of the entire T-cell population, of the helper/inducer T-cell subset, and of the cytotoxic/suppressor T-cell subset have been identified, using mouse monoclonal antibodies obtained from Dr. P. Kung. Various T-cell populations were radio-labelled, the
J D Nuckols et al.
Journal of cutaneous pathology, 26(4), 169-175 (1999-05-21)
Differentiation between mycosis fungoides (MF) and cutaneous inflammatory processes can usually be made on clinical and histologic grounds. In difficult cases, immunohistochemical studies can be helpful since MF infiltrates usually contain a predominance of CD4+ lymphocytes, while most inflammatory lesions
D Y Mason et al.
Journal of clinical pathology, 45(12), 1084-1088 (1992-12-01)
To evaluate whether cytotoxic/suppressor T cells can be detected in paraffin wax embedded human tissue samples using antibodies to a synthetic CD8 peptide sequence. Polyclonal and monoclonal antibodies were raised against a 13 amino acid peptide sequence from the cytoplasmic

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