PHR1611

Mercaptopurine

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinonimo/i: 6-Mercaptopurine monohydrate, 6-Purinethiol, 6-Thiohypoxanthine
• Formula empirica (notazione di Hill): C₅H₄N₄S·H₂O
• Numero CAS: 6112-76-1
• Peso molecolare: 170.19
• Beilstein: 4012091
• Numero CE: 200-037-4
• Numero MDL: MFCD03854445
• Codice UNSPSC: 41116107
• ID PubChem: 329823508
• NACRES: NA.24

Proprietà

• Grado: certified reference material; pharmaceutical secondary standard
• Livello qualitativo: 300
• agenzia: traceable to BP 773; traceable to USP 1392002
• Famiglia di API: mercaptopurine
• CdA: current certificate can be downloaded
• Confezionamento: pkg of 1 g
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: O.S=C1NC=Nc2nc[nH]c12
• InChI: 1S/C5H4N4S.H2O/c10-5-3-4(7-1-6-3)8-2-9-5;/h1-2H,(H2,6,7,8,9,10);1H2; WFFQYWAAEWLHJC-UHFFFAOYSA-N
• Informazioni sul gene: human ... PPAT(5471)

Descrizione

Descrizione generale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Mercaptopurine is an anticancer and an immunosuppressive drug employed for the management of acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn′s disease, etc. Its mode of action involves interference in the nucleic acid synthesis by the inhibition of purine metabolism.

Applicazioni

Mercaptopurine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations, suspensions, and double drug liposomes by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAC3476 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H301,H341,H361fd
• Consigli di prudenza: P202 - P264 - P280 - P301 + P310 - P405 - P501
• Classi di pericolo: Acute Tox. 3 Oral - Muta. 2 - Repr. 2
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3