PHL89700

Harmaline

phyproof^® Reference Substance

• Sinonimo/i: 1-Methyl-7-methoxy-3,4-dihydro-β-carboline, 3,4-Dihydroharmine, 4,9-Dihydro-7-methoxy-1-methyl-3H-pyrido[3,4-b]indole, Dihydroharmine, Harmalol methyl ether, Harmidine, NSC 407285
• Formula empirica (notazione di Hill): C₁₃H₁₄N₂O
• Numero CAS: 304-21-2
• Peso molecolare: 214.26
• Beilstein: 207310
• Numero MDL: MFCD00004955
• Codice UNSPSC: 41116107
• NACRES: NA.24

Proprietà

• Grado: primary reference standard
• Nome Commerciale: phyproof^® Reference Substance
• Saggio: ≥95.0% (HPLC)
• Produttore/marchio commerciale: PhytoLab
• drug control: stupéfiant (France); regulated under CDSA - not available from Sigma-Aldrich Canada
• Punto di fusione: 232-234 °C (lit.)
• applicazioni: food and beverages
• Formato: neat
• Stringa SMILE: COc1ccc2c3CCN=C(C)c3[nH]c2c1
• InChI: 1S/C13H14N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-4,7,15H,5-6H2,1-2H3; RERZNCLIYCABFS-UHFFFAOYSA-N

Descrizione

Descrizione generale

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Applicazioni

Reactant for preparation of:

• Acylated harmalines via Friedel-Crafts reaction
• Phenacyl derivatives of 1-methyl-7-methoxy-β-carbolines as central nervous system affectors
• Palladium harmaline DMSO chloro complex as anti-tumor agent

Natural product scaffold in preparation of:

• Trypanothione reductase inhibitors†

Azioni biochim/fisiol

CNS stimulant; may act through NMDA receptors

Note legali

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Informazioni sulla sicurezza

• Pittogrammi: GHS08,GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302,H371
• Consigli di prudenza: P260 - P264 - P301 + P312 - P308 + P311 - P405 - P501
• Classi di pericolo: Acute Tox. 4 Oral - STOT SE 2
• Organi bersaglio: Central nervous system
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable