LIGHTOX19

LightOx^™19

≥95% (HPLC)

• Formula empirica (notazione di Hill): C₂₃H₂₃NO₂
• Numero CAS: 2324152-25-0
• Peso molecolare: 345.43
• Codice UNSPSC: 12352101
• NACRES: NA.22

Proprietà

• Saggio: ≥95% (HPLC)
• Stato: powder
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: N1(c2c(cc(cc2)C#Cc3ccc(cc3)C(=O)O)C(C=C1)(C)C)C(C)C
• InChI: HXWVRWZLWIKKOS-UHFFFAOYSA-N

Descrizione

Applicazioni

Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.

Azioni biochim/fisiol

Strong ligand for retinoic acid receptor proteins

Caratteristiche e vantaggi

LightOx19 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx19 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Altre note

Chemical Equivalency 1ea=1mg

Note legali

LightOx is a trademark of LightOx Ltd.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable