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Key Documents

53541

Supelco

Tulobuterol

VETRANAL®, analytical standard

Sinonimo/i:

2-tert-Butylamino-1-(2-chlorophenyl)ethanol

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About This Item

Formula empirica (notazione di Hill):
C12H18ClNO · HCl
Numero CAS:
Peso molecolare:
264.19
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Nome Commerciale

VETRANAL®

Saggio

≥98.0% (HPLC)

tecniche

HPLC: suitable
gas chromatography (GC): suitable
solid phase extraction (SPE): suitable

applicazioni

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

Cl.CC(C)(C)NCC(O)c1ccccc1Cl

InChI

1S/C12H18ClNO.ClH/c1-12(2,3)14-8-11(15)9-6-4-5-7-10(9)13;/h4-7,11,14-15H,8H2,1-3H3;1H
RSLNRVYIRDVHLY-UHFFFAOYSA-N

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Descrizione generale

Standard for Supelco MIP SPE cartridges. For more information request Supelco Literature T407075, T706019, T706030, T706020
Tulobuterol hydrochloride is a sympathomimetic amine, possessing bronchodilator activity.

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tulobuterol hydrochloride may be used as a reference standard in determining the concentration of tulobuterol hydrochloride present in bovine liver homogenates and urine samples using gas chromatography coupled with tandem mass spectrometry (GC-MS-MS).

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Note legali

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Ki-Seok Kim et al.
Colloids and surfaces. B, Biointerfaces, 76(2), 404-409 (2009-12-26)
In this work, porous poly(epsilon-caprolactone) (PCL)/Eudragit RS 100 (ERS-100) microcapsules containing tulobuterol base as a model drug were prepared by a solvent evaporation method and the effect of the quaternary ammonium groups of ERS-100 on the release behaviors of the
Tetsuo Watanabe et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 131(10), 1483-1492 (2011-10-04)
The purpose of this study was to compare the transdermal transfer profiles of brand and generic tulobuterol patch formulations and to evaluate possible changes of in vivo kinetics resulting from increased transdermal transfer by means of pharmacokinetic analysis using reported
Chiyohiko Shindoh et al.
The Tohoku journal of experimental medicine, 218(4), 271-278 (2009-07-30)
Tulobuterol, a sympathomimetic drug used as a transdermal patch, increases normal diaphragm muscle strength. Because diaphragm muscle weakness (i.e. decrease of contraction) is a feature of bronchial asthma and sepsis, we examined the in vitro and in vivo effects of
Tetsuya Abe et al.
Pulmonary pharmacology & therapeutics, 24(5), 617-624 (2011-06-22)
The addition of transdermal tulobuterol (Tulo) to inhaled tiotropium bromide (Tio) produced beneficial effects on spirometry-assessed parameters of respiratory function, disease-related symptoms and quality of life in patients with chronic obstructive pulmonary disease (COPD). To compare the effects of Tio
Ki-Seok Kim et al.
Colloids and surfaces. B, Biointerfaces, 80(2), 240-246 (2010-07-14)
pH sensitive Pluronic F127 (PF127)/poly(acrylic acid) (PAAc) hydrogels containing tulobuterol-loaded silica were prepared with PF127 content. The effects of the PF127 content and silica on the sustained release behaviors of the PAAc hydrogels were investigated. The results showed that the

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