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Supelco

Mettler-Toledo Calibration substance ME 51143091, Saccharin

traceable to primary standards (LGC)

Sinonimo/i:

Saccharin, 2,3-Dihydroxy-1,2-benzisothiazol-3-one-1,1-dioxide, 2-Sulfobenzoic acid imide, o-Benzoic sulfimide

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About This Item

Formula empirica (notazione di Hill):
C7H5NO3S
Numero CAS:
Peso molecolare:
183.18
Beilstein:
6888
Numero CE:
Numero MDL:
Codice UNSPSC:
20121904
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Qualità

traceable to primary standards (LGC)

Durata

limited shelf life, expiry date on the label

Punto di fusione

226-229 °C (lit.)

applicazioni

food and beverages
pharmaceutical

Formato

neat

Stringa SMILE

O=C1NS(=O)(=O)c2ccccc12

InChI

1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)
CVHZOJJKTDOEJC-UHFFFAOYSA-N

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Descrizione generale

Mettler-Toledo calibration substance ME 51143091, saccharin is an analytical standard, designed for the routine calibration of Mettler-Toledo melting point instrument. Its value is an average of 6 to 12 measurements with a Mettler-Toledo MP90 Excellence instrument that is calibrated against primary standards. The melting point is validated by Capillary method as per European Pharmacopeia (2.2.14.)

Applicazioni

Saccharin Mettler-Toledo calibration substance ME 51143091 is a melting point calibration standard used to calibrate Mettler-Toledo mp instruments.

Azioni biochim/fisiol

A sweet tastant for mammals. A glycerol taste receptor binding site specific for glucose has been proposed in drosophila.

Caratteristiche e vantaggi

  • Traceable to a primary standard from LGC, London
  • Melting point evaluation conducted in both thermodynamic and pharmacopeia modes for physically correct and heating rate dependent melting point determinations, respectively
  • Available with certificates of analysis and safety data sheet
  • A product of analytical standard grade to help meet the QC/QA requirements of melting point determination
  • Uncertainty of measurement up to ± 0.3 °C

Note legali

Mettler-Toledo is a registered trademark of Mettler-Toledo, Inc.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Physiology & behavior, 109, 33-41 (2012-12-04)
In a recent study, intragastric (IG) self-infusion of 16% glucose stimulated 1-h intake and conditioned a preference for a flavored saccharin solution in C57BL/6J mice (Zukerman et al., 2011). Experiment 1 of the present study presents a concentration-response analysis of
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Many chemicals are known to exhibit endocrine activity and affect reproductive functions in vertebrates and invertebrates. Endocrine effects include influences on sexual differentiation of the brain during development and reproductive and non-reproductive behavior in adult offspring. We previously demonstrated that
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Molecular pharmaceutics, 9(9), 2605-2612 (2012-08-08)
Cocrystals constitute an important class of pharmaceutical solids for their remarkable ability to modulate solubility and pH dependence of water insoluble drugs. Here we show how cocrystals of indomethacin-saccharin (IND-SAC) and carbamazepine-saccharin (CBZ-SAC) enhance solubility and impart a pH-sensitivity different
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