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Key Documents

32936

Supelco

Fumonisin B1

reference material, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Sinonimo/i:

Fumonisin B1 from Fusarium moniliforme, Macrofusine

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About This Item

Formula empirica (notazione di Hill):
C34H59NO15
Numero CAS:
Peso molecolare:
721.83
Numero MDL:
Codice UNSPSC:
85151701
ID PubChem:
NACRES:
NA.24

Grado

analytical standard
reference material

Durata

limited shelf life, expiry date on the label

Produttore/marchio commerciale

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

cleaning products
cosmetics
food and beverages
personal care

Formato

neat

Temperatura di conservazione

−20°C

Stringa SMILE

CCCC[C@@H](C)[C@@H](OC(=O)C[C@@H](CC(O)=O)C(O)=O)[C@H](C[C@@H](C)C[C@H](O)CCCC[C@@H](O)C[C@H](O)[C@H](C)N)OC(=O)C[C@@H](CC(O)=O)C(O)=O

InChI

1S/C34H59NO15/c1-5-6-9-20(3)32(50-31(44)17-23(34(47)48)15-29(41)42)27(49-30(43)16-22(33(45)46)14-28(39)40)13-19(2)12-24(36)10-7-8-11-25(37)18-26(38)21(4)35/h19-27,32,36-38H,5-18,35H2,1-4H3,(H,39,40)(H,41,42)(H,45,46)(H,47,48)/t19-,20+,21-,22+,23+,24+,25+,26-,27-,32+/m0/s1
UVBUBMSSQKOIBE-DSLOAKGESA-N

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Descrizione generale

Fumonisins are a family of mycotoxins that are characterized by their structurally related homologs. They are generally produced by fungi of Fusarium species.

Applicazioni

Fumonisin B1 may be used as an analytical reference standard for the determination of the analyte in:
  • Swine liver by high performance liquid chromatography-fluorescence detection (HPLC-FLD).
  • Cereals by HPLC.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

Fungal metabolite believed to cause leukoencephalomalacia in horses.

Risultati analitici

purity : ≥92.5% (HPLC)

Pittogrammi

Skull and crossbonesHealth hazard

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 3 Oral - Carc. 2 - Repr. 2 - STOT RE 2

Organi bersaglio

Kidney,Liver

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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Certificati d'analisi (COA)

Lot/Batch Number

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Simple method for the simultaneous isolation and determination of fumonisin B1 and its metabolite aminopentol-1 in swine liver by liquid chromatography-fluorescence detection.
Pagliuca G, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 819(1), 97-103 (2005)
Influence of experimental parameters on the fluorescence response and recovery of the high-performance liquid chromatography analysis of fumonisin B1.
Samapundo S, et al.
Journal of Chromatography A, 1109(2), 312-316 (2006)
J M Soriano et al.
Progress in lipid research, 44(6), 345-356 (2005-11-04)
Fumonisins are a group of mycotoxins produced primarily by Fusarium moniliforme. Several fumonisins have been isolated through out the years but only fumonisin B1, B2 and B3 are the ones present in naturally contaminated foods, with B1 being the most
Anil A Chuturgoon et al.
Toxicology letters, 227(1), 50-55 (2014-03-13)
Fumonisin B₁ (FB₁), a common mycotoxin contaminant of maize, is known to inhibit sphingolipid biosynthesis and has been implicated in hepatocellular carcinoma promoting activity in humans and animals. MicroRNAs (miRNA) are small noncoding RNAs that regulate gene expression via translational
Ronald T Riley et al.
Molecular nutrition & food research, 56(9), 1445-1455 (2012-07-21)
Fumonisins (FB) are mycotoxins found in maize. The purpose of this study was to (i) determine the relationship between FB(1) , FB(2) , and FB(3) intake and urinary excretion in humans, (ii) validate a method to isolate urinary FB on

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