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22192

Supelco

Cellulose Chromatography Resin

acetate phthalate

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About This Item

Formula empirica (notazione di Hill):
C116H116O64
Numero CAS:
9004-38-0
Peso molecolare:
2534.12
Numero MDL:
MFCD00072769
Codice UNSPSC:
12000000
NACRES:
SB.52

product name

Cellulose acetate phthalate,

Forma fisica

powder

Livello qualitativo

200

tecniche

LPLC: suitable

Matrice

acetylated cellulose

Gruppo funzionale matrice

phthalate

Capacità

1.0 meq/mL

Tecnica di separazione

reversed phase

InChI

1S/C32H34O19/c1-13(33)45-11-19-21(35)25(49-29(42)17-9-5-3-7-15(17)27(38)39)23(37)32(48-19)51-24-20(12-46-14(2)34)47-31(44)26(22(24)36)50-30(43)18-10-6-4-8-16(18)28(40)41/h3-10,19-26,31-32,35-37,44H,11-12H2,1-2H3,(H,38,39)(H,40,41)/t19-,20-,21-,22+,23-,24-,25+,26-,31-,32+/m1/s1
DMNFZTKVDDFCQE-WJXNTJCASA-N

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Descrizione generale

Cellulose acetate phthalate (CAP) is a microbicide which inactivates sexually transmitted disease (STD) pathogens like HIV-1. CAP has been used for enteric film coating of tablets and capsules.

Applicazioni

CAP is used as a stabiling agent in the preparation of Pseudolatex.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
BCCD4766
BCBW5667
BCBN9248V
BCBK8299V
BCBK3366V

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Sigma-Aldrich

C1052

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Sigma-Aldrich

180963

Cellulose acetate butyrate

Cellulose acetate average Mn ~30,000 by GPC

Sigma-Aldrich

180955

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Cellulose acetate butyrate average Mn ~30,000

Sigma-Aldrich

419060

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Hypromellose phthalate European Pharmacopoeia (EP) Reference Standard

Y0000915

Hypromellose phthalate

D Quintanar-Guerrero et al.
International journal of pharmaceutics, 188(2), 155-164 (1999-10-16)
Pseudolatexes were obtained by a new process based on an emulsification-diffusion technique involving partially water-miscible solvents. The preparation method consisted of emulsifying an organic solution of polymer (saturated with water) in an aqueous solution of a stabilizing agent (saturated with
A Robert Neurath et al.
BMC infectious diseases, 3, 27-27 (2003-11-18)
Cellulose acetate phthalate (CAP) has been used for several decades in the pharmaceutical industry for enteric film coating of oral tablets and capsules. Micronized CAP, available commercially as "Aquateric" and containing additional ingredients required for micronization, used for tablet coating
A Robert Neurath et al.
BMC infectious diseases, 2, 6-6 (2002-05-02)
Cellulose acetate phthalate (CAP), a promising candidate microbicide for prevention of sexual transmission of the human immunodeficiency virus type 1 (HIV-1) and other sexually transmitted disease (STD) pathogens, was shown to inactivate HIV-1 and to block the coreceptor binding site
C J Lacey et al.
International journal of STD & AIDS, 21(10), 714-717 (2010-12-09)
We carried out a phase 1 trial of a candidate vaginal microbicide gel against HIV-1 and other sexually transmitted diseases, which contained cellulose acetate 1,2-benzenedicarboxylate (also known as cellulose acetate phthalate) in a glycerol-based vehicle. We had to terminate the
James C DiNunzio et al.
Molecular pharmaceutics, 5(6), 968-980 (2009-05-13)
Amorphous engineered particle compositions of itraconazole (ITZ) and potential concentration enhancing polymers, cellulose acetate phthalate (CAP) and polyvinyl acetate phthalate (PVAP), were produced by ultra-rapid freezing to investigate the effect of these polymers on the bioavailability of ITZ solid dispersions.
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