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MTH17MAG-47K

Millipore

MILLIPLEX® Mouse TH17 Magnetic Bead Panel - Immunology Multiplex Assay

Simultaneously analyze multiple Th17 cytokine and chemokine biomarkers with the Th17 Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples.

Sinonimo/i:

Luminex® Mouse Immunology Panel, Millipore Mouse Immunology Panel, Mouse Immunology Protein Multiplex Assay

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About This Item

Codice UNSPSC:
12161503
eCl@ss:
32161000
NACRES:
NA.84

Livello qualitativo

Reattività contro le specie

mouse

Produttore/marchio commerciale

Milliplex®

assay range

linearity: 111.0%
(1:04)

linearity: 113.1%
(1:08)

standard curve range: 1.5-1,500 pg/mL
(IL-4)

standard curve range: 10-10,000 pg/mL
(IL-17F)

standard curve range: 127-130,000 pg/mL
(IL-28B)

standard curve range: 15-15,000 pg/mL
(IL-1β)

standard curve range: 2.4-2,500 pg/mL
(IL-22)

standard curve range: 20-20,000 pg/mL
(IL-10, IL-12(p70), & IL-21)

standard curve range: 3.4-3,500 pg/mL
(TNFα)

standard curve range: 34-35,000 pg/mL
(GM-CSF & IL-15)

standard curve range: 342-350,000 pg/mL
(IL-23)

standard curve range: 39-40,000 pg/mL
(IL-13 & IL-17A)

standard curve range: 4.9-5,000 pg/mL
(IL-5)

standard curve range: 488-500,000 pg/mL
(TNFβ)

standard curve range: 49-50,000 pg/mL
(CD40L IL-31 & MIP-3α)

standard curve range: 586-600,000 pg/mL
(IL-17E/ IL-25)

standard curve range: 6.9-6,000 pg/mL
(IL-2)

standard curve range: 7.8-8,000 pg/mL
(IFNγ & IL-6)

standard curve range: 78-80,000 pg/mL
(IL-33)

standard curve range: 879-900,000 pg/mL
(IL-27)

tecniche

multiplexing: suitable

Metodo di rivelazione

fluorometric (Luminex xMAP)

Condizioni di spedizione

wet ice

Descrizione generale

The MILLIPLEX® Mouse Th17 Bead panel enables you to focus on the therapeutic potential of the modulation of CD4 T-helper cell cytokines. Coupled with the Luminex® xMAP®platform in a bead format, you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of dozens of analytes simultaneously, which can dramatically improve productivity.

Panel Type: Cytokines/Chemokines

Specificità

Cross Reactivty
There was no or minimum cross-reactivity between the antibodies and any other analytes in the panel (see details in assay protocol).

Applicazioni

  • Analytes: CD40 Ligand, GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12 (p70), IL-13, IL-15, IL-17A, IL-17E/IL-25, IL-17F, IL-21, IL-22, IL-23, IL-27, IL-28B, IL-31, IL-33, MIP-3α/CCL20, TNF-α, TNFβ
  • Recommended Sample type: serum, plasma or tissue/cell lysate and culture supernatant
  • Recommended Sample dilution: neat
  • Assay Run Time: overnight or one day
  • Research Category: Inflammation & Immunology

Caratteristiche e vantaggi

Design your multiplex kit by choosing available analytes within this panel.

Stoccaggio e stabilità

Recommended storage for kit components is 2 - 8°C.

Altre note

Sensitivity: Refer to kit protocol for sensitivities of individual biomarkers.

Note legali

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Avvertenze

Danger

Classi di pericolo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

Organi bersaglio

Respiratory Tract

Codice della classe di stoccaggio

10 - Combustible liquids


Certificati d'analisi (COA)

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Mohammad Afzal Khan et al.
Frontiers in immunology, 9, 1010-1010 (2018-06-09)
Microvascular injury during acute rejection has been associated with massive infiltration of CD4+ T effector cells, and the formation of complement products (C3a and C5a). Regulatory T cells (Tregs) are potent immunosuppressors of the adaptive immune system and have proven
M John Albert et al.
Scientific reports, 9(1), 12024-12024 (2019-08-21)
There is no information on cytokine profiles for use as markers of protection in Campylobacter jejuni infection. To study this, we used outer membrane protein (MOMP [PorA]) as the vaccine for protection and spleen cell cytokines as markers of protection.
Mohammad Afzal Khan et al.
Cells, 10(5) (2021-06-03)
Interleukin-10 plays a vital role in maintaining peripheral immunotolerance and favors a regulatory immune milieu through the suppression of T effector cells. Inflammation-induced microvascular loss has been associated with airway epithelial injury, which is a key pathological source of graft
Anthony Tam et al.
Cells, 11(19) (2022-10-15)
Genome-wide association studies (GWAS) have shown that variants of patched homolog 1 (PTCH1) are associated with lung function abnormalities in the general population. It has also been shown that sonic hedgehog (SHH), an important ligand for PTCH1, is upregulated in
Ting-Jing Shen et al.
Frontiers in cellular and infection microbiology, 10, 557610-557610 (2020-10-20)
Dengue virus (DENV) infection in the brain causes severe dengue disease with neuropathic complications. In addition to viral effects, immunogenic or pathogenic central nervous system (CNS) inflammation can be induced during DENV infection. By using an immunocompetent outbred ICR (Institute

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