MABS419

Anti-BMPR-1A, clone 4B7B2 Antibody

ascites fluid, clone 4B7B2, from mouse

• Sinonimo/i: Bone morphogenetic protein receptor type-1A, BMP type-1A receptor, BMPR-1A
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Forma dell’anticorpo: ascites fluid
• Tipo di anticorpo: primary antibodies
• Clone: 4B7B2, monoclonal
• Reattività contro le specie: mouse, human
• tecniche: ELISA: suitable; flow cytometry: suitable; immunohistochemistry: suitable; western blot: suitable
• Isotipo: IgG1
• N° accesso UniProt: P36894
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... BMPR1A(657)

Descrizione

Descrizione generale

BMPR-1A (bone morphogenic protein receptor type 1A) signaling is known to be important for inner root sheath differentiation, hair follicle cycling and tooth development. Mutations in BMPR-1A are a common cause of juvenile polyposis syndrome (JPS). BMPR-1A is expressed in a high quantity during the formation of the primary and secondary palate and the loss of BMPR-1A could be a cause for the cleft palate birth defect.

Immunogeno

Purified recombinant fragment of human BMPR1A expressed in E. Coli

Applicazioni

Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected BMPR-1A in colon cancer and kidney tissues.

Flow Cytometry Analysis: A 1;200-400 dilution from a representative lot detected BMPR-1A in HeLa cells.

ELISA: A representative lot detected control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).

Research Category
Signaling

Research Sub Category
Developmental Signaling

This Anti-BMPR-1A, clone 4B7B2 Antibody is validated for use in western blotting, IHC, flow cytometry & ELISA for the detection of BMPR-1A.

Qualità

Evaluated by Western Blotting in PC-3, K562 and mouse liver lysates.

Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected BMPR-1A in PC-3, K562 and mouse liver lysates.

Descrizione del bersaglio

~65 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Stato fisico

Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.

Unpurified

Stoccaggio e stabilità

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable